ENSC
ENSYSCE BIO (ENSC)
NASDAQ
$0.27-$0.001 (-0.37%)
Price as of Jun 23, 2026 7:55 PM EDT
  • $4.2M
    Market Cap
  • -87.18%
    1-Year Change
  • Biotechnology
    Industry

Key Performance

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  • Earnings Score: N/A
  • Momentum Score: 59
  • True Yield: N/A
  • Financial Health Score: N/A
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Latest Research & News

Tiny Pain-Focused Biotech Ensysce Biosciences Surges Amid Strategic Review

Ensysce Biosciences (NASDAQ: ENSC) shares surged 58.66% to $0.63 on Friday after the company announced a strategic review of alternatives aimed at enhancing shareholder value. The Board is exploring partnerships, licensing arrangements, or asset sales to advance its proprietary TAAP and MPAR platforms for safer opioid medicines.

02/27/2026, 12:10 PM • Benzinga

Follow-Through Leaders: Production Ramps, AI Alliances, Balance Sheet Strength

Several companies are transitioning from strategic announcements to operational execution. Kraig Biocraft Laboratories has begun production of recombinant spider silk and received National Geographic cover feature. Rackspace and Palantir announced a strategic partnership to deploy enterprise AI in production environments. Ensysce Biosciences initiated a formal strategic review to explore partnerships and enhance shareholder value.

02/27/2026, 9:45 AM • GlobeNewswire

Chronic and Acute Pain Clinical Trial Pipeline Analysis: 150+ Key Companies Shaping the Future of Chronic and Acute Pain Therapeutics | DelveInsight

DelveInsight released a comprehensive analysis of the chronic and acute pain clinical trial pipeline, identifying 150+ active companies developing 200+ pipeline drugs across various clinical stages. The report highlights a shift toward non-opioid, targeted, and multimodal approaches due to growing concerns about opioid dependence. Recent developments include FDA orphan drug designation for Adolore BioTherapeutics' gene therapy, positive Phase IIb results for Dogwood Therapeutics' Halneuron, and Phase III publication of Vertanical's VER-01 for chronic low back pain.

01/28/2026, 1:00 PM • GlobeNewswire

Diamond Equity Research Releases Update Note on Ensysce Biosciences, Inc. (NASDAQ: ENSC)

Ensysce Biosciences advanced multiple clinical initiatives in Q2 2025, including launching a Phase 3 trial for PF614, completing enrollment in an overdose prevention study, and receiving a patent notice for its OUD program.

08/15/2025, 8:00 AM • GlobeNewswire

Ensysce Biosciences Narrows Loss in Q2

Ensysce Biosciences reported Q2 2025 results, advancing its PF614 opioid program to Phase 3 and achieving milestones in overdose-protection studies. The company reported a narrower GAAP loss of $(0.79) per share, with revenue primarily from federal grants.

08/13/2025, 6:22 PM • The Motley Fool

Peers

Statistics

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Day Range
$0.27
$0.28
$0.27
1-Year Range
$0.25
$2.57
$0.27
Latest Close$0.27
Change
+$0.002 (+0.62%)
Volume947,688
Market Cap$4.2M
Shares Outstanding15.4M
P/E (TTM)-0.09
Diluted EPS (TTM)-$3.01
Enterprise Value$3.9M

Information as of 06/22/2026

Company Profile

ENSYSCE BIOSCIENCES INC
ENSYSCE BIOSCIENCES INC
https://www.ensysce.com
$4.2M
Market Cap
-$11.8M
Net Income
Sector: Healthcare
Industry: Biotechnology
7946 Ivanhoe Avenue, La Jolla, CA, United States, 92037
858 263 4196

Ensysce Biosciences, Inc., a clinical-stage pharmaceutical company, develops prescription drugs for severe pain relief in opioid misuse, abuse, and overdose in the United States. It develops products using Trypsin Activated Abuse Protection (TAAP) platform, designed to release clinically effective drugs only when exposed to specific physiological conditions; and Multi-Pill Abuse Resistance (MPAR) platform, an over-dose protection opioid prodrug technology. The company's lead product candidate is PF614, a TAAP oxycodone prodrug candidate for the treatment of severe or chronic pain; and PF614-MPAR, a combination product of PF614 and nafamostat for overdose protection. It is also developing PF8001 and PF8026 are extended and immediate-release prodrugs of amphetamine for attention deficit hyperactivity disorder; and PF9001 to treat opioid use disorder. Ensysce Biosciences, Inc. was founded in 2003 and is based in La Jolla, California.

Key Executives

  • D. Lynn Kirkpatrick
  • David C. Humphrey
  • Geoffrey Birkett
  • William K. Schmidt
  • Linda Pestano

Current Ownership Distribution

  • Insiders12.2M (43.35%)
  • Institutions12.2M (43.11%)
  • Mutual Funds3.8M (13.54%)
  • Other0 (0.00%)