Key Performance
More- Earnings Score: N/A
- Momentum Score: 9
- True Yield: N/A
- Financial Health Score: N/A
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Latest Research & News
Pliant Therapeutics presented updated Phase 1 trial data for PLN-101095, an integrin inhibitor combined with pembrolizumab, showing encouraging results in immune checkpoint inhibitor-refractory patients. The drug demonstrated confirmed responses with 89% average tumor reduction and 19-month median time on treatment. The company has initiated a Phase 1b expansion trial with interim data expected in 2027.
04/18/2026, 1:31 PM • GlobeNewswire
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Company Profile
Pliant Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on discovering and developing integrin-based therapeutics for the treatment of solid tumors. The company's lead product candidate is the PLN-101095, an oral, small molecule dual inhibitor of avß8 and avß1 integrins that is in Phase 1a/1b for the treatment of solid tumors. It is also developing drug discovery platform comprising proprietary library of over 15,000 integrin binding molecules, focusing on integrin-based target-mediated drug delivery. Pliant Therapeutics, Inc. was incorporated in 2015 and is headquartered in South San Francisco, California.