SPRO
SPERO THERAPETCS (SPRO)
NASDAQ
$2.28+$0.10 (+4.59%)
Price as of Jul 14, 2026 8:34 AM EDT
  • $126.2M
    Market Cap
  • -17.42%
    1-Year Change
  • Biotechnology
    Industry

Key Performance

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  • Earnings Score: N/A
  • Momentum Score: 51
  • True Yield: N/A
  • Financial Health Score: N/A
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Latest Research & News

Spero Therapeutics and Innovent Biologics Announce Exclusive License for SP001 (IBI355), a Phase 2-Ready Third-Generation Anti-CD40L Antibody

Spero Therapeutics and Innovent Biologics announced an exclusive license agreement for SP001 (IBI355), a third-generation anti-CD40L antibody. Spero receives global rights excluding Greater China, with potential milestone payments totaling approximately $1.1 billion plus tiered royalties. Spero plans to initiate a Phase 2 trial in IgG4-related disease in Q2 2027, while Innovent will pursue a Phase 2 trial in Sjögren's disease in China by early 2027.

07/14/2026, 6:00 AMGlobeNewswire

GSK, Spero Win FDA Nod For First-Ever Oral Carbapenem Antibiotic For Complicated UTIs

GSK and Spero Therapeutics announced FDA approval of Utebzi (tebipenem pivoxil hydrobromide), the first oral carbapenem antibiotic for treating complicated urinary tract infections including pyelonephritis. The drug demonstrated non-inferiority to intravenous imipenem-cilastatin in Phase 3 trials and is expected to launch in the U.S. by end of 2026, offering an alternative to hospital-based IV treatments for the 3+ million Americans annually affected by cUTIs.

06/17/2026, 1:29 PMBenzinga

Spero Therapeutics Announces Inducement Grant Under Nasdaq Listing Rule 5635(c)(4)

Spero Therapeutics granted 90,000 restricted stock unit awards to a new employee under their 2019 Inducement Equity Incentive Plan, with vesting occurring in four equal annual installments starting December 1, 2025.

11/28/2025, 8:00 AMGlobeNewswire

Peers

Statistics

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Day Range
$2.07
$2.19
$2.18
1-Year Range
$1.83
$2.98
$2.18
Latest Close$2.18
Change
+$0.08 (+3.67%)
Volume703,993
Market Cap$126.2M
Shares Outstanding57.9M
P/E (TTM)8.51
Diluted EPS (TTM)$0.26
Enterprise Value$70.2M

Information as of 07/13/2026

Company Profile

SPERO THERAPEUTICS INC
SPERO THERAPEUTICS INC
https://sperotherapeutics.com
$126.2M
Market Cap
$15.2M
Net Income
Sector: Healthcare
Industry: Biotechnology
675 Massachusetts Avenue, Cambridge, MA, United States, 02139
857 242 1600

Spero Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on identifying and developing novel treatments for multi-drug resistant (MDR) bacterial infections and rare diseases in the United States. The company's product candidates include Tebipenem HBr (tebipenem pivoxil hydrobromide), an oral carbapenem-class antibiotic to treat complicated urinary tract infections, including pyelonephritis for adult patients, which has completed second Phase 3 trial. It has license agreement with Meiji Seika Pharma Co., Ltd. to develop, manufacture, and commercialize tebipenem pivoxil and tebipenem HBr; and Everest Medicines to develop, manufacture, and commercialize SPR206 in Greater China, South Korea, and Southeast Asian countries. Spero Therapeutics, Inc. was incorporated in 2013 and is headquartered in Cambridge, Massachusetts.

Key Executives

  • Esther Rajavelu
  • Timothy Keutzer
  • Sheila Finan
  • John Raymond

Current Ownership Distribution

  • Mutual Funds329.3M (50.43%)
  • Institutions296.4M (45.40%)
  • Insiders27.2M (4.17%)
  • Other0 (0.00%)