Key Performance
More- Earnings Score: N/A
- Momentum Score: 41
- True Yield: N/A
- Financial Health Score: N/A
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Latest Research & News
AC Immune announced Phase 1 trial results showing its TDP-43 PET tracer ACI-19626 demonstrates significantly higher uptake in ALS patients compared to healthy controls, with detection in brain regions expected to accumulate TDP-43 pathology. The tracer showed good safety, tolerability, and suitable pharmacokinetic profile for brain imaging. Part 2 of the trial has begun with potential expansion to include up to 30 patients with FTD, ALS, or LATE.
05/22/2026, 7:00 AM • GlobeNewswire
AC Immune Announces Amendment to Morphomer ® Tau License and Collaboration Agreement with Lilly
AC Immune and Eli Lilly have amended their 2018 collaboration agreement to advance new Tau Morphomer small molecule candidates for Alzheimer's disease treatment. AC Immune will receive a CHF10 million upfront payment and additional milestone payments, with IND-enabling studies expected to commence in H1 2026. The amendment reflects progress in targeting intracellular Tau pathology.
04/07/2026, 7:00 AM • GlobeNewswire
AC Immune reported promising interim Phase 2 trial results for ACI-7104.056, an active immunotherapy targeting alpha-synuclein, showing potential to slow Parkinson's disease progression with a strong safety profile and 100% antibody responder rate.
12/11/2025, 7:00 AM • GlobeNewswire
AC Immune Reports Third Quarter 2025 Financial Results and Provides a Corporate Update
AC Immune reported Q3 2025 financial results, highlighting a strategic refocus on high-value neurodegenerative disease assets, reducing workforce by 30%, and maintaining cash resources until Q3 2027. The company is progressing multiple clinical-stage immunotherapy and small molecule programs targeting neurodegenerative diseases.
11/04/2025, 7:00 AM • GlobeNewswire
AC Immune Sharpens Pipeline Focus with Operational Efficiencies Extending Cash Runway
AC Immune is reducing workforce by 30% to focus on late-stage clinical development of neurodegenerative disease therapies, extending cash runway to Q3 2027 and maintaining key clinical milestones.
09/04/2025, 3:45 AM • GlobeNewswire
AC Immune Reports Second Quarter 2025 Financial Results and Provides a Corporate Update
AC Immune reported Q2 2025 financial results, highlighting progress in neurodegenerative disease therapies with three active immunotherapies in Phase 2 clinical development and a cash balance of CHF 127.1 million providing funding into Q1 2027.
08/05/2025, 7:00 AM • GlobeNewswire
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MoreInformation as of 06/02/2026
Company Profile
AC Immune SA, a clinical stage biopharmaceutical company, discovers, designs, and develops medicines, and therapeutic and diagnostic products for the prevention and treatment of neurodegenerative diseases associated with protein misfolding. The company's SupraAntigen and Morphomer platforms are designed to generate biologics and small molecules, which selectively interact with misfolded proteins that are common in a range of neurodegenerative diseases. It develops Crenezumab, a humanized, conformation specific monoclonal antibody used to slow Alzheimer's disease (AD) progression; and Semorinemab, an investigational monoclonal anti-Tau antibody that targets the N-terminal portion of the Tau protein and is designed to bind to Tau and slow its spread between neurons for the treatment of AD. The company is also developing ACI-24.060 for the treatment of down syndrome related AD; ACI-7104.056 to treat Parkinson's disease; and ACI-35.030, designs to stimulate a patient's immune system to produce antibodies against pathological phosphorylated Tau. In addition, it develops diagnostic programs consisting of PI-2620, a Tau diagnostic for AD, as well as non-AD Tauopathies; and ACI-12589 and ACI-15916, a-sync PET tracer that supports the differential diagnosis of multiple system atrophy from other neurodegenerative diseases. Further, the company is researching and developing Morphomer Tau aggregation inhibitors to evaluate candidates in AD; Morphomer a-syn to compete with small molecule inhibitors of a-syn aggregation; and NeuroOrphan Tauopathies. Additionally, it generates discovery and preclinical stage molecules targeting range of neurodegenerative diseases, which include diagnostics targeting TDP-43, alpha-synuclein, and NLRP3. The company has license agreements and collaborations with Genentech, Inc.; Janssen Pharmaceuticals, Inc.; Life Molecular Imaging SA; and Eli Lilly and Company. AC Immune SA was incorporated in 2003 and is headquartered in Lausanne, Switzerland.