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- $219.3MMarket Cap
- 286.73%1-Year Change
- BiotechnologyIndustry
ALX ONCOLOGY (ALXO)
Key Performance
More- Earnings Score: N/A
- Momentum Score: 65
- True Yield: N/A
- Financial Health Score: N/A
Latest Research & News
ALX Oncology reported Q4 2025 financial results with improved net losses and announced strong clinical progress for its lead candidates evorpacept and ALX2004. The company validated CD47 as a predictive biomarker for evorpacept response in cancer trials, completed a $150 million equity offering extending cash runway through H1 2028, and appointed Barbara Klencke as permanent Chief Medical Officer. Multiple clinical milestones are anticipated over the next 12-18 months.
02/27/2026, 8:00 AM • GlobeNewswire
ALX Oncology to Present at the 44th Annual J.P. Morgan Healthcare Conference
ALX Oncology announced its participation in the 44th Annual J.P. Morgan Healthcare Conference, with CEO Jason Lettmann and CMO Barbara Klencke delivering a corporate presentation on January 15, 2026. The clinical-stage biotech company is advancing evorpacept, a CD47-inhibitor being evaluated across multiple cancer indications, and ALX2004, an EGFR-targeted antibody-drug conjugate in Phase 1 trials.
01/08/2026, 11:00 AM • GlobeNewswire
ALX Oncology reported impressive results from a Phase 2 trial combining evorpacept with rituximab and lenalidomide in treating indolent non-Hodgkin lymphoma, achieving a 92% complete response rate and 100% overall response rate.
12/07/2025, 8:00 AM • GlobeNewswire
The HER2-positive gastric cancer market is experiencing sustained growth, with over 20 companies developing novel targeted therapies, driven by advances in precision medicine and expanded HER2 testing.
11/27/2025, 1:00 PM • GlobeNewswire
ALX Oncology to Present at Upcoming Investor Conferences
ALX Oncology will participate in two healthcare conferences in November and December 2025, presenting their ongoing clinical-stage cancer therapies, including lead candidate evorpacept and new pipeline candidate ALX2004.
11/18/2025, 11:00 AM • GlobeNewswire
Revolution Medicines appointed Alan Sandler, M.D. as chief development officer and added regional general managers in the U.S. and Europe to support potential approvals of RAS-targeted cancer therapies.
09/29/2025, 9:00 AM • GlobeNewswire
The gastric cancer treatment market is expected to grow positively by 2034, driven by advances in targeted therapies and immunotherapies, with emerging drugs from multiple pharmaceutical companies showing promise in treating HER2-positive and advanced gastric cancers.
08/11/2025, 1:00 PM • GlobeNewswire
Peers
Statistics
MoreInformation as of 06/23/2026
Company Profile
ALX Oncology Holdings Inc., a clinical-stage immuno-oncology company, focuses on developing therapies for cancer patients in the United States. The company's lead product candidate is Evorpacept, a CD47 blocking therapeutic biologic development as a combination therapy with other anti-cancer agents, including ASPEN-06, under phase 2 clinical study for treating Gastric/GEJ cancer. It has collaboration agreement for Evorpacept combination programs comprising Jazz Pharmaceuticals plc for zanidatamab, under phase 1b/2 trial for the treatment of breast cancer and other solid tumors; HER2 with an ADC, fam-trastuzumab deruxtecan-nxki, under phase 1 trial for the treatment of patients with breast cancer; ALX2004, under phase 1 clinical trial for treating solid tumors; MD Anderson Cancer Center with rituximab and lenalidomide for the treatment of patients with indolent and aggressive NHL; and Sanofi with isatuximab and dexamethasone, under phase 1/2 trial for the treatment of patients with relapsed or refractory multiple myeloma. It has license agreements with Board of Trustees of Leland Stanford Junior University. The company was incorporated in 2015 and is headquartered in South San Francisco, California.
Key Executives
- Jason W. Lettmann
- Harish Shantharam
- Shelly Wong
- Barbara J. Klencke
- Jeff E. Knight
Current Ownership Distribution
- Institutions747.8M (80.57%)
- Mutual Funds162.9M (17.55%)
- Insiders17.4M (1.88%)
- Other0 (0.00%)