AMLX
AMYLYX PHARM (AMLX)
NASDAQ
$16.36+$0.07 (+0.46%)
Price as of Jun 23, 2026 4:40 PM EDT
  • $1.8B
    Market Cap
  • 224.30%
    1-Year Change
  • Drug Manufacturers - Specialty & Generic
    Industry

Top Holders

Institutional
Mutual Funds
Holder
Ownership %
Shares Held
Change (Shares, %)
Report Date
FMR LLC
20.01%
16.6M
+112,122 (+0.67%)
Mar 31, 2026
BLACKROCK, INC.
10.62%
8.8M
-225,595 (-2.56%)
Mar 31, 2026
PERCEPTIVE ADVISORS LLC
9.97%
8.3M
0 (0.00%)
Mar 31, 2026
TCG CROSSOVER MANAGEMENT, LLC
7.51%
6.2M
0 (0.00%)
Mar 31, 2026
VANGUARD GROUP INC
6.98%
5.8M
+531,162 (+9.15%)
Dec 31, 2025
COMMODORE CAPITAL LP
6.80%
5.7M
0 (0.00%)
Mar 31, 2026
JANUS HENDERSON GROUP PLC
6.00%
5.0M
+520,201 (+10.43%)
Mar 31, 2026

Current Ownership Distribution

  • Institutions1.0B (82.01%)
  • Mutual Funds208.5M (16.56%)
  • Insiders18.0M (1.43%)
  • Other0 (0.00%)

Insider Transactions

  • 1.43% (18.0M)
    Current InsiderOwnership (%, shares)
  • 1
    Number of InsiderBuying (last 12 months)
  • $684,750.00
    Amount of InsiderBuying (last 12 months)
  • 5
    Number of InsiderSelling (last 12 months)
  • $476.4M
    Amount of InsiderSelling (last 12 months)
Insider Name & Title
Type
Date
Transaction Value
Shares
Share Price
Shares After Transactions
Klee Justin B.
Co-Chief Executive Officer
Award
Mar 05, 2026
$0.00
373,295
$0.00
373,295
Cohen Joshua B
Co-Chief Executive Officer
Award
Mar 05, 2026
$0.00
373,295
$0.00
373,295
Mazzariello Gina
Chief Legal Officer
Award
Mar 05, 2026
$0.00
111,990
$0.00
111,990
FRATES JAMES M
Chief Financial Officer
Award
Mar 05, 2026
$0.00
143,985
$0.00
143,985
Klee Justin B.
Co-Chief Executive Officer
Award
Mar 05, 2026
$0.00
248,865
$0.00
3.6M
Cohen Joshua B
Co-Chief Executive Officer
Award
Mar 05, 2026
$0.00
248,865
$0.00
3.6M
Mazzariello Gina
Chief Legal Officer
Award
Mar 05, 2026
$0.00
74,660
$0.00
209,090
FRATES JAMES M
Chief Financial Officer
Award
Mar 05, 2026
$0.00
95,990
$0.00
261,628
Mazzariello Gina
Chief Legal Officer
Sell
Mar 02, 2026
$99,378.30
6,844
$14.52
134,430
FRATES JAMES M
Chief Financial Officer
Sell
Feb 02, 2026
$52,096.89
3,557
$14.65
173,547
Cohen Joshua B
Co-Chief Executive Officer
Sell
Feb 02, 2026
$227,592.70
15,500
$14.68
3.4M
Klee Justin B.
Co-Chief Executive Officer
Sell
Feb 02, 2026
$227,617.50
15,500
$14.69
3.4M
Mazzariello Gina
Chief Legal Officer
Sell
Feb 02, 2026
$50,515.61
3,448
$14.65
144,693
Klee Justin B.
Co-Chief Executive Officer
Exempt
Jan 16, 2026
$0.00
2,847
$0.00
0
Klee Justin B.
Co-Chief Executive Officer
Exempt
Jan 16, 2026
$21,551.79
2,847
$7.57
3.4M
Klee Justin B.
Co-Chief Executive Officer
Sell
Jan 16, 2026
$27,701.17
1,995
$13.89
3.4M
Klee Justin B.
Co-Chief Executive Officer
Exempt
Jan 15, 2026
$1.5M
197,153
$7.57
3.5M
Klee Justin B.
Co-Chief Executive Officer
Sell
Jan 15, 2026
$1.8M
136,193
$13.58
3.4M
Klee Justin B.
Co-Chief Executive Officer
Exempt
Jan 15, 2026
$0.00
197,153
$0.00
2,847
MILNE GEORGE M JR
Gift
Jan 12, 2026
$0.00
17,780
$0.00
812,881
Klee Justin B.
Co-Chief Executive Officer
Sell
Jan 06, 2026
$85,589.44
7,715
$11.09
3.3M
Cohen Joshua B
Co-Chief Executive Officer
Sell
Jan 06, 2026
$85,596.38
7,715
$11.09
3.3M
FRATES JAMES M
Chief Financial Officer
Sell
Jan 06, 2026
$36,953.86
3,326
$11.11
177,104
Firestone Karen
Buy
Dec 23, 2025
$100,845.00
8,100
$12.45
63,100
Mazzariello Gina
Chief Legal Officer
Sell
Sep 30, 2025
$128,668.98
8,828
$14.58
148,141
Klee Justin B.
Co-Chief Executive Officer
Sell
Sep 30, 2025
$427,950.12
29,775
$14.37
3.3M
FRATES JAMES M
Chief Financial Officer
Sell
Sep 30, 2025
$154,650.42
10,558
$14.65
280,430
Cohen Joshua B
Co-Chief Executive Officer
Sell
Sep 30, 2025
$426,469.34
29,733
$14.34
3.3M
Klee Justin B.
Co-Chief Executive Officer
Sell
Sep 30, 2025
$3,002.00
200
$15.01
3.3M
Bedrosian Camille L
Chief Medical Officer
Sell
Sep 30, 2025
$175,517.78
12,039
$14.58
182,336