AMLX
AMYLYX PHARM (AMLX)
NASDAQ
$39.34+$0.68 (+1.76%)
Price as of Aug 21, 2026 7:55 PM EDT
  • $4.3B
    Market Cap
  • 315.70%
    1-Year Change
  • Drug Manufacturers - Specialty & Generic
    Industry

Top Holders

Institutional
Mutual Funds
Holder
Ownership %
Shares Held
Change (Shares, %)
Report Date
FMR LLC
15.04%
16.7M
+97,368 (+0.58%)
Jun 30, 2026
BLACKROCK, INC.
7.94%
8.8M
-1,751 (-0.02%)
Jun 30, 2026
PERCEPTIVE ADVISORS LLC
7.50%
8.3M
+50,000 (+0.60%)
Jun 30, 2026
TCG CROSSOVER MANAGEMENT, LLC
5.62%
6.2M
0 (0.00%)
Jun 30, 2026
VANGUARD GROUP INC
5.22%
5.8M
+531,162 (+9.15%)
Dec 31, 2025
COMMODORE CAPITAL LP
5.08%
5.7M
0 (0.00%)
Jun 30, 2026
N/A
4.71%
5.2M
+5.2M (+100.00%)
Jun 30, 2026

Current Ownership Distribution

  • Institutions1.2B (81.62%)
  • Mutual Funds238.2M (16.87%)
  • Insiders21.4M (1.52%)
  • Other0 (0.00%)

Insider Transactions

  • 1.52% (21.4M)
    Current InsiderOwnership (%, shares)
  • 1
    Number of InsiderBuying (last 12 months)
  • $684,750.00
    Amount of InsiderBuying (last 12 months)
  • 5
    Number of InsiderSelling (last 12 months)
  • $480.1M
    Amount of InsiderSelling (last 12 months)
Insider Name & Title
Type
Date
Transaction Value
Shares
Share Price
Shares After Transactions
Klee Justin B.
Co-Chief Executive Officer
Award
Aug 18, 2026
$0.00
60,039
$0.00
3.6M
Mazzariello Gina
Chief Legal Officer
Award
Aug 18, 2026
$0.00
21,284
$0.00
200,374
FRATES JAMES M
Chief Financial Officer
Award
Aug 18, 2026
$0.00
22,807
$0.00
244,435
Cohen Joshua B
Co-Chief Executive Officer
Award
Aug 18, 2026
$0.00
60,039
$0.00
3.6M
Mazzariello Gina
Chief Legal Officer
Sell
Jul 10, 2026
$264,121.50
15,000
$17.61
179,090
Mazzariello Gina
Chief Legal Officer
Sell
Jul 09, 2026
$274,746.00
15,000
$18.32
194,090
FRATES JAMES M
Chief Financial Officer
Award
Mar 05, 2026
$0.00
143,985
$0.00
143,985
Mazzariello Gina
Chief Legal Officer
Award
Mar 05, 2026
$0.00
111,990
$0.00
111,990
Cohen Joshua B
Co-Chief Executive Officer
Award
Mar 05, 2026
$0.00
373,295
$0.00
373,295
Klee Justin B.
Co-Chief Executive Officer
Award
Mar 05, 2026
$0.00
373,295
$0.00
373,295
FRATES JAMES M
Chief Financial Officer
Award
Mar 05, 2026
$0.00
95,990
$0.00
261,628
Mazzariello Gina
Chief Legal Officer
Award
Mar 05, 2026
$0.00
74,660
$0.00
209,090
Cohen Joshua B
Co-Chief Executive Officer
Award
Mar 05, 2026
$0.00
248,865
$0.00
3.6M
Klee Justin B.
Co-Chief Executive Officer
Award
Mar 05, 2026
$0.00
248,865
$0.00
3.6M
Mazzariello Gina
Chief Legal Officer
Sell
Mar 02, 2026
$99,378.30
6,844
$14.52
134,430
Klee Justin B.
Co-Chief Executive Officer
Sell
Feb 02, 2026
$227,617.50
15,500
$14.69
3.4M
Cohen Joshua B
Co-Chief Executive Officer
Sell
Feb 02, 2026
$227,592.70
15,500
$14.68
3.4M
FRATES JAMES M
Chief Financial Officer
Sell
Feb 02, 2026
$52,096.89
3,557
$14.65
173,547
Mazzariello Gina
Chief Legal Officer
Sell
Feb 02, 2026
$50,515.61
3,448
$14.65
144,693
Klee Justin B.
Co-Chief Executive Officer
Exempt
Jan 16, 2026
$21,551.79
2,847
$7.57
3.4M
Klee Justin B.
Co-Chief Executive Officer
Sell
Jan 16, 2026
$27,701.17
1,995
$13.89
3.4M
Klee Justin B.
Co-Chief Executive Officer
Exempt
Jan 16, 2026
$0.00
2,847
$0.00
0
Klee Justin B.
Co-Chief Executive Officer
Exempt
Jan 15, 2026
$1.5M
197,153
$7.57
3.5M
Klee Justin B.
Co-Chief Executive Officer
Sell
Jan 15, 2026
$1.8M
136,193
$13.58
3.4M
Klee Justin B.
Co-Chief Executive Officer
Exempt
Jan 15, 2026
$0.00
197,153
$0.00
2,847
MILNE GEORGE M JR
Gift
Jan 12, 2026
$0.00
17,780
$0.00
812,881
Klee Justin B.
Co-Chief Executive Officer
Sell
Jan 06, 2026
$85,589.44
7,715
$11.09
3.3M
Cohen Joshua B
Co-Chief Executive Officer
Sell
Jan 06, 2026
$85,596.38
7,715
$11.09
3.3M
FRATES JAMES M
Chief Financial Officer
Sell
Jan 06, 2026
$36,953.86
3,326
$11.11
177,104
Firestone Karen
Buy
Dec 23, 2025
$100,845.00
8,100
$12.45
63,100