AMLX
AMYLYX PHARM (AMLX)
NASDAQ
$30.61-$1.19 (-3.75%)
Price as of Nov 12, 2026 9:35 AM EST
  • $4.1B
    Market Cap
  • 157.91%
    1-Year Change
  • Drug Manufacturers - Specialty & Generic
    Industry

Top Holders

Institutional
Mutual Funds
Holder
Ownership %
Shares Held
Change (Shares, %)
Report Date
FMR LLC
15.51%
19.9M
+3.2M (+16.13%)
Sep 30, 2026
BLACKROCK, INC.
6.87%
8.8M
-1,751 (-0.02%)
Jun 30, 2026
PERCEPTIVE ADVISORS LLC
6.48%
8.3M
+50,000 (+0.60%)
Jun 30, 2026
TCG CROSSOVER MANAGEMENT, LLC
4.86%
6.2M
0 (0.00%)
Jun 30, 2026
VANGUARD GROUP INC
4.52%
5.8M
+531,162 (+9.15%)
Dec 31, 2025
COMMODORE CAPITAL LP
4.39%
5.7M
0 (0.00%)
Jun 30, 2026
N/A
4.07%
5.2M
+5.2M (+100.00%)
Jun 30, 2026

Current Ownership Distribution

  • Institutions1.2B (79.28%)
  • Mutual Funds286.4M (19.23%)
  • Insiders22.2M (1.49%)
  • Other0 (0.00%)

Insider Transactions

  • 1.49% (22.2M)
    Current InsiderOwnership (%, shares)
  • 1
    Number of InsiderBuying (last 12 months)
  • $684,750.00
    Amount of InsiderBuying (last 12 months)
  • 5
    Number of InsiderSelling (last 12 months)
  • $792.3M
    Amount of InsiderSelling (last 12 months)
Insider Name & Title
Type
Date
Transaction Value
Shares
Share Price
Shares After Transactions
FRATES JAMES M
Chief Financial Officer
Sell
Sep 10, 2026
$315,194.80
9,768
$32.27
234,667
Mazzariello Gina
Chief Legal Officer
Sell
Sep 10, 2026
$309,139.59
9,525
$32.46
190,849
Bedrosian Camille L
Chief Medical Officer
Sell
Sep 10, 2026
$256,003.86
7,947
$32.21
280,145
Mazzariello Gina
Chief Legal Officer
Sell
Sep 10, 2026
$366.74
11
$33.34
190,838
Klee Justin B.
Co-Chief Executive Officer
Sell
Sep 10, 2026
$932,552.93
29,025
$32.13
3.6M
Cohen Joshua B
Co-Chief Executive Officer
Sell
Sep 10, 2026
$950,040.16
29,545
$32.16
3.6M
Bedrosian Camille L
Chief Medical Officer
Sell
Sep 10, 2026
$68,864.24
2,081
$33.09
278,064
Cohen Joshua B
Co-Chief Executive Officer
Sell
Sep 10, 2026
$30,463.75
919
$33.15
3.6M
FRATES JAMES M
Chief Financial Officer
Sell
Sep 10, 2026
$34,625.87
1,042
$33.23
233,625
Klee Justin B.
Co-Chief Executive Officer
Sell
Sep 10, 2026
$47,710.33
1,439
$33.16
3.6M
Firestone Karen
Exempt
Aug 31, 2026
$0.00
25,000
$0.00
0
Firestone Karen
Exempt
Aug 31, 2026
$0.00
25,000
$0.00
0
Firestone Karen
Exempt
Aug 31, 2026
$44,000.00
25,000
$1.76
91,900
Firestone Karen
Exempt
Aug 31, 2026
$126,250.00
25,000
$5.05
116,900
FRATES JAMES M
Chief Financial Officer
Award
Aug 18, 2026
$0.00
22,807
$0.00
244,435
Klee Justin B.
Co-Chief Executive Officer
Award
Aug 18, 2026
$0.00
60,039
$0.00
3.6M
Mazzariello Gina
Chief Legal Officer
Award
Aug 18, 2026
$0.00
21,284
$0.00
200,374
Cohen Joshua B
Co-Chief Executive Officer
Award
Aug 18, 2026
$0.00
60,039
$0.00
3.6M
Mazzariello Gina
Chief Legal Officer
Sell
Jul 10, 2026
$264,121.50
15,000
$17.61
179,090
Mazzariello Gina
Chief Legal Officer
Sell
Jul 09, 2026
$274,746.00
15,000
$18.32
194,090
FRATES JAMES M
Chief Financial Officer
Award
Mar 05, 2026
$0.00
143,985
$0.00
143,985
Mazzariello Gina
Chief Legal Officer
Award
Mar 05, 2026
$0.00
111,990
$0.00
111,990
Cohen Joshua B
Co-Chief Executive Officer
Award
Mar 05, 2026
$0.00
373,295
$0.00
373,295
Klee Justin B.
Co-Chief Executive Officer
Award
Mar 05, 2026
$0.00
373,295
$0.00
373,295
FRATES JAMES M
Chief Financial Officer
Award
Mar 05, 2026
$0.00
95,990
$0.00
261,628
Mazzariello Gina
Chief Legal Officer
Award
Mar 05, 2026
$0.00
74,660
$0.00
209,090
Cohen Joshua B
Co-Chief Executive Officer
Award
Mar 05, 2026
$0.00
248,865
$0.00
3.6M
Klee Justin B.
Co-Chief Executive Officer
Award
Mar 05, 2026
$0.00
248,865
$0.00
3.6M
Mazzariello Gina
Chief Legal Officer
Sell
Mar 02, 2026
$99,378.30
6,844
$14.52
134,430
Klee Justin B.
Co-Chief Executive Officer
Sell
Feb 02, 2026
$227,617.50
15,500
$14.69
3.4M