Key Performance
More- Earnings Score: N/A
- Momentum Score: 44
- True Yield: N/A
- Financial Health Score: N/A
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Latest Research & News
Boundless Bio presented preclinical data supporting BBI-940, an oral kinesin degrader, as a potential first-in-class therapy for advanced or metastatic breast cancers. The compound targets a novel kinesin protein essential for extrachromosomal DNA (ecDNA) segregation in cancer cells but non-essential in healthy cells. Preclinical studies demonstrated tumor regressions in ecDNA-positive breast cancer models, with the Phase 1 KOMODO-1 clinical trial currently enrolling patients with ER+/HER2- and TNBC-LAR breast cancers.
04/17/2026, 4:49 PM • GlobeNewswire
Boundless Bio Reports Fourth Quarter and Full Year 2025 Financial Results and Business Highlights
Boundless Bio announced financial results for 2025 with $107.6 million in cash providing runway through mid-2028. The company's lead program BBI-940, a first-in-class oral Kinesin degrader, is actively enrolling patients in the KOMODO-1 trial for ER+/HER2- breast cancer and TNBC-LAR. The company reduced R&D expenses to $44.8 million for 2025 and narrowed net losses to $58.2 million. Boundless ceased enrollment in the POTENTIATE trial to prioritize BBI-940 development.
03/09/2026, 7:00 AM • GlobeNewswire
Boundless Bio to Participate in the Guggenheim Emerging Outlook: Biotech Summit 2026
Boundless Bio announced that its novel Kinesin degrader BBI-940 received IND acceptance, with first-in-human clinical trials expected to begin in the first half of 2026. The company extended its operating runway through portfolio prioritization, including discontinuation of the POTENTIATE trial. CEO Zachary Hornby will participate in upcoming biotech industry conferences.
02/05/2026, 7:00 AM • GlobeNewswire
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Company Profile
Boundless Bio, Inc., a clinical-stage oncology company, develops interrogating extrachromosomal DNA (ecDNA) directed therapies for treating patients with oncogene amplified cancers. Its lead product candidate is BBI-940, an ecDNA-directed therapeutic candidate (ecDTx) that is in Phase 1/2 clinical trial in patients with estrogen receptor positive and human epidermal growth factor receptor 2 negative breast cancer, as well as patients with triple-negative breast cancer luminal androgen receptor subtype. The company was formerly known as Pretzel Therapeutics, Inc. and changed its name to Boundless Bio, Inc. in July 2019. Boundless Bio, Inc. was incorporated in 2018 and is headquartered in San Diego, California.