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- $312.8MMarket Cap
- -41.30%1-Year Change
- BiotechnologyIndustry
CABALETTA BIO (CABA)
Key Performance
More- Earnings Score: 30
- Momentum Score: 37
- True Yield: N/A
- Financial Health Score: 72
Latest Research & News
The Idiopathic Inflammatory Myositis (IIM) market is projected to grow at 16.8% CAGR through 2036, reaching significant expansion driven by rising disease awareness, improved diagnostics, and an expanding pipeline of targeted therapies. The market was valued at USD 714 million across the 7MM in 2025, with the US accounting for 55% of the market. Multiple pharmaceutical companies are advancing investigational treatments addressing unmet medical needs in dermatomyositis, polymyositis, and inclusion body myositis.
11/10/2026, 1:00 PM • GlobeNewswire
Cabaletta Bio announced positive Phase 1/2 clinical data for resecabtagene autoleucel (rese-cel), a CAR T cell therapy for autoimmune diseases. Results showed 100% of dermatomyositis patients maintained immunomodulator-free responses through one year, 100% of lupus nephritis patients achieved remission, and 71% of systemic sclerosis patients achieved improvement. The therapy demonstrated a favorable safety profile across 71 patients. Cabaletta anticipates topline results from the registrational dermatomyositis cohort in 2H27 and BLA submission in 1Q28.
11/08/2026, 10:00 AM • GlobeNewswire
The lupus nephritis market is projected to grow at a 7% CAGR through 2036, driven by increasing disease awareness, improved diagnosis, and expanding adoption of targeted therapies. The market was valued at USD 2.1 billion in 2025 across seven major markets. Three therapies have received FDA approval (belimumab, voclosporin, and obinutuzumab), while a robust pipeline of innovative treatments including CAR-T therapies, complement inhibitors, and monoclonal antibodies is expected to transform disease management.
09/14/2026, 1:00 PM • GlobeNewswire
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MoreInformation as of 11/10/2026
Company Profile
Cabaletta Bio, Inc., a clinical-stage biotechnology company, focuses on the discovery and development of engineered T cell therapies for patients with autoimmune diseases. The company's lead product candidate is resecabtagene autoleucel, a 4-1BB co-stimulatory domain-containing fully human CD19-CAR T, which is in Phase 1/2 clinical trials for the treatment of dermatomyositis, anti-synthetase syndrome, immune-mediated necrotizing myopathy, juvenile myositis, lupus nephritis, systemic lupus erythematosus, relapsing and progressive multiple sclerosis, mucocutaneous and mucosal pemphigus vulgaris (PV), systemic sclerosis, and generalized myasthenia gravis. It also develops DSG3-CAART, a CAAR T cell therapy that is in Phase 1 clinical trial for the treatment of mucosal PV; and MuSK-CAART, an investigational cell therapy in Phase 1 trial for treating patients with anti-muscle-specific kinase (MuSK) antibody positive myasthenia gravis. It has collaborations with the University of Pennsylvania and the Children's Hospital of Philadelphia; Nanjing IASO Biotherapeutics Co., Ltd; Oxford Biomedica; Autolus Holdings (UK) Limited; and WuXi Advanced Therapies, Inc. The company was formerly known as Tycho Therapeutics, Inc. and changed its name to Cabaletta Bio, Inc. in August 2018. Cabaletta Bio, Inc. was incorporated in 2017 and is headquartered in Philadelphia, Pennsylvania.
Key Executives
- Steven A. Nichtberger
- David J. Chang FACR
- Gwendolyn K. Binder
- Anup Marda
- Aimee Payne
Current Ownership Distribution
- Institutions950.9M (78.16%)
- Mutual Funds260.7M (21.43%)
- Insiders5.0M (0.41%)
- Other0 (0.00%)