CNTA
CENTESSA SP ADS (CNTA)
NASDAQ
$40.71+$0.53 (+1.32%)
Price as of Jun 23, 2026 4:39 PM EDT
  • $6.2B
    Market Cap
  • 209.08%
    1-Year Change
  • Biotechnology
    Industry

Key Performance

More
  • Earnings Score: N/A
  • Momentum Score: 83
  • True Yield: N/A
  • Financial Health Score: N/A
TradeSmith Loading

Latest Research & News

$HAREHOLDER ALERT: The M&A Class Action Firm Continues to Investigate the Merger—RAMP, NEE, CNTA, and HCBN

Monteverde & Associates PC is investigating four merger transactions: LiveRamp Holdings' sale to Publicis Groupe for $38.50/share, NextEra Energy's merger with Dominion Energy, Centessa Pharmaceuticals' acquisition by Eli Lilly for $38.00/share plus contingent value rights, and HCB Financial's merger with Independent Bank Corporation. The firm is seeking shareholders to join class action lawsuits related to these deals.

05/27/2026, 10:53 AM • GlobeNewswire

Nxera Pharma Operational Highlights and Consolidated Results for the First Quarter 2026

Nxera Pharma reported strong Q1 2026 results with revenue of JPY 11.3 billion, a significant increase from the prior year, driven by seven R&D milestone events. The company signed a licensing agreement with Santhera for vamorolone in APAC markets, achieved positive Phase 3 results for daridorexant in South Korea, and received milestone payments from Neurocrine and AbbVie. Additionally, Centessa Pharmaceuticals (spun out from Nxera in 2019) agreed to be acquired by Eli Lilly for up to $7.8 billion, with Nxera retaining rights to milestone and royalty payments.

05/01/2026, 2:36 AM • GlobeNewswire

Forget Weight Loss Drugs: Here's An Even Better Reason to Invest in Eli Lilly

While Eli Lilly is known for its weight loss drug dominance with Zepbound and Mounjaro, the article highlights the company's underappreciated diversification across oncology, immunology, and neuroscience. With blockbuster drugs like Verzenio ($5.7B sales) and Taltz ($3.6B sales), plus strategic acquisitions in gene therapy and other areas, Eli Lilly is better positioned than competitors like Novo Nordisk to weather competition and drive long-term growth beyond its current weight-loss market leadership.

04/27/2026, 8:15 PM • The Motley Fool

Is This $6.3 Billion Deal a Game Changer for Eli Lilly?

Eli Lilly announced a $6.3 billion acquisition of U.K.-based Centessa Pharmaceuticals, a clinical-stage biotech focused on neuroscience. The deal includes up to $1.5 billion in milestone payments tied to Centessa's lead drug candidate cleminorexton for sleep-wake disorders. Despite the large price tag, Lilly's stock reacted positively due to the company's strong financial position, bolstered by the success of weight-loss drugs Zepbound and Mounjaro. The acquisition represents Lilly's strategy of both building and acquiring assets for continued growth.

04/16/2026, 9:30 AM • The Motley Fool

Looks Like M&A Week in 3 Different Sectors

A major M&A week sees Sysco acquiring Restaurant Depot for $26 billion and McCormick merging with Unilever's food division for $44 billion, while Eli Lilly acquires Centessa Pharmaceuticals for $7.8 billion. The podcast discusses the track record of consumer brand mergers (mostly unsuccessful) and analyzes Whirlpool as a dividend investment amid housing market headwinds.

04/08/2026, 12:02 PM • The Motley Fool

Deal Dispatch: McCormick, Unilever Merge, Sysco Acquires Jetro Restaurant Depot For $29 Billion, QVC Considers Bankruptcy

Major M&A activity dominates the market with McCormick merging with Unilever's Foods business in a $29.1 billion deal, Sysco acquiring Jetro Restaurant Depot for $29 billion, and Eli Lilly acquiring Centessa Pharmaceuticals for $7.8 billion. Meanwhile, QVC faces financial distress and is considering Chapter 11 bankruptcy, while several other companies including IO Biotech and Lipella Pharmaceuticals have filed for bankruptcy.

04/03/2026, 10:35 AM • Benzinga

Lilly’s Next Empire: A $10 Billion Bet on AI and Neuroscience

Eli Lilly commits over $10 billion to two major strategic initiatives: a $2.75 billion expanded partnership with InSilico Medicine to leverage AI for drug discovery, and a $6.3-7.8 billion acquisition of Centessa Pharmaceuticals to enter the sleep-wake disorders market. These moves aim to modernize R&D processes, diversify revenue beyond its GLP-1 franchise, and support the company's premium valuation.

04/02/2026, 1:51 PM • Investing

Nxera Pharma's Partner Centessa Pharmaceuticals to be Acquired by Lilly

Eli Lilly and Company has agreed to acquire Centessa Pharmaceuticals, which developed an OX2R agonist pipeline for sleep-wake disorders in collaboration with Nxera Pharma. Nxera retains material economic interests including milestone payments, royalties, and an equity stake in Centessa. The acquisition validates Nxera's drug discovery platform and complements Nxera's existing multi-target collaboration with Lilly worth up to $694 million in potential milestones.

03/31/2026, 7:43 PM • Benzinga

Nxera Pharma’s Partner Centessa Pharmaceuticals to be Acquired by Lilly

Eli Lilly has agreed to acquire Centessa Pharmaceuticals, which is developing an OX2R agonist pipeline for sleep-wake disorders jointly discovered with Nxera. Nxera retains milestone payments, royalties, and an equity interest in Centessa under the transaction. Nxera also maintains a separate collaboration with Lilly on metabolic disease drug discovery.

03/31/2026, 7:43 PM • GlobeNewswire

Eli Lilly Expands Into Sleep Medicine With Centessa Buyout

Eli Lilly agreed to acquire Centessa Pharmaceuticals for approximately $6.3 billion upfront plus up to $1.5 billion in contingent payments. The acquisition expands Lilly's neuroscience portfolio with Centessa's orexin receptor 2 agonist pipeline, including the lead candidate cleminorexton for sleep disorders. The deal is expected to close in Q3 pending shareholder and regulatory approval. Centessa shares surged 45% on the announcement.

03/31/2026, 10:48 AM • Benzinga

Forget Centessa Pharmaceuticals: This Rare‑Disease Specialist Has a Superior Portfolio and Pipeline

While Centessa Pharmaceuticals shows promise with its ORX750 narcolepsy candidate, the article argues that Vertex Pharmaceuticals is a superior investment choice. Vertex has an established profitable business in cystic fibrosis, recent successful launches like Journavx and Casgevy, and a strong late-stage pipeline including zimislecel for Type 1 diabetes. Centessa, as a pre-revenue biotech, carries significantly higher risk despite its promising pipeline.

02/26/2026, 1:30 PM • The Motley Fool

Biotech Fund Dumps 1.85 Million Centessa Shares as Stock Jumps Over 50%

Commodore Capital significantly reduced its stake in Centessa Pharmaceuticals by selling 1.85 million shares (worth ~$46.86 million) in Q4, cutting its position from over 9% to 1.66% of assets. The sale comes as CNTA stock has surged 53.4% over the past year. The fund's move suggests capital redeployment amid Centessa's strategic shift toward focusing on its orexin franchise under new CEO Mario Accardi, raising questions about concentration risk versus the potential of the company's narrowed pipeline.

02/23/2026, 10:09 AM • The Motley Fool

Nxera Pharma to Receive $1.8 Million Milestone Payment from Centessa Pharmaceuticals

Nxera Pharma announced that its research collaboration partner Centessa Pharmaceuticals achieved an early development milestone with ORX489, an orexin receptor 2 agonist for neuropsychiatric disorders. The achievement triggers a $1.8 million milestone payment to Nxera, which will be recognized as revenue in Q1 2026.

02/12/2026, 3:45 AM • GlobeNewswire

This Fund Locked In Gains With a $14.5 Million Biotech Exit Amid a Staggering Stock Rally

Tanager Wealth Management exited its entire position in Centessa Pharmaceuticals (CNTA), selling 598,044 shares for approximately $14.5 million in the fourth quarter. The biotech stock had surged nearly 57% over the past year, significantly outperforming the S&P 500. The fund's exit reflects a strategy to reduce oversized positions after sharp rallies, despite Centessa's improving fundamentals including strong cash reserves and a recent CEO transition.

02/01/2026, 7:09 PM • The Motley Fool

Centessa Pharmaceuticals Announces Poster Presentation of New Preclinical Data Supporting Expansion of Orexin Receptor 2 (OX2R) Agonist Pipeline into Neuropsychiatric Indications at the 64th ACNP Annual Meeting

Centessa Pharmaceuticals presented preclinical data at the 64th ACNP Annual Meeting showing that OX2R activation with their agonist CNT-9982 reduced behavioral despair and enhanced wakefulness in animal models of major depressive disorder. The company plans to expand its OX2R agonist pipeline beyond rare hypersomnias into additional neuropsychiatric indications with high unmet clinical need.

01/14/2026, 5:00 PM • GlobeNewswire

Peers

Statistics

More
Day Range
$39.98
$40.18
$40.18
1-Year Range
$13.00
$40.18
$40.18
Latest Close$40.18
Change
+$0.16 (+0.40%)
Volume3,758,569
Market Cap$6.2B
Shares Outstanding154.7M
P/E (TTM)-22.58
Diluted EPS (TTM)-$1.78
Enterprise Value$6.3B

Information as of 06/22/2026

Company Profile

CENTESSA PHARMACEUTICALS PLC
CENTESSA PHARMACEUTICALS PLC
https://centessa.com
$6.2B
Market Cap
-$250.6M
Net Income
Sector: Healthcare
Industry: Biotechnology
1 Ashley Road, Altrincham, United Kingdom, WA14 2DT
44 617 4685770

Centessa Pharmaceuticals plc, together with its subsidiaries, discovers, develops, and delivers orexin-based neuroscience therapeutics in the United Kingdom and the United States. The company develops ORX750, an orexin receptor 2 agonist, which is in Phase IIa clinical trial for the treatment of central disorders of hypersomnolence, including narcolepsy type 1 and 2, as well as idiopathic hypersomnia. It also engages in the development of ORX142 which is in Phase I clinical trial for the treatment of neurological and neurodegenerative disorders; ORX489 which is in Phase I clinical trial for the treatment of neuropsychiatric disorders; and LockBody, an early-stage immuno-oncology program technology platform. The company was incorporated in 2020 and is headquartered in Altrincham, the United Kingdom.

Key Executives

  • Mario Alberto Accardi
  • John J. Crowley
  • Stephen J. Kanes
  • Iqbal J. Hussain
  • Gregory Weinhoff

Current Ownership Distribution

  • Institutions1.7B (92.25%)
  • Mutual Funds132.2M (6.99%)
  • Insiders14.4M (0.76%)
  • Other0 (0.00%)