CRDF
CARDIFF ONCOLOGY (CRDF)
NASDAQ
$1.44+$0.04 (+3.14%)
Price as of Jun 03, 2026 7:57 PM EDT
  • $129.9M
    Market Cap
  • -56.98%
    1-Year Change
  • Biotechnology
    Industry

Key Performance

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  • Earnings Score: N/A
  • Momentum Score: 30
  • True Yield: N/A
  • Financial Health Score: N/A
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Latest Research & News

Cardiff Oncology Announces Webcast to Discuss Updated Phase 2 CRDF-004 Data for Onvansertib in First-Line RAS-Mutated mCRC

Cardiff Oncology announced updated Phase 2 CRDF-004 data for onvansertib, a PLK1 inhibitor, will be presented at ASCO 2026 on June 2, 2026, with an investor webcast scheduled for June 3, 2026. The company has selected the 30 mg dose of onvansertib in combination with FOLFIRI/bevacizumab for advancement into a registrational Phase 3 trial for first-line RAS-mutated metastatic colorectal cancer, following positive dose-dependent improvements in response rates and progression-free survival.

05/21/2026, 5:00 PMGlobeNewswire

Cardiff Oncology to Present Updated Phase 2 Data of Onvansertib in First-Line RAS-Mutated mCRC in a Rapid Oral Session at ASCO 2026

Cardiff Oncology announced it will present updated interim data from its Phase 2 CRDF-004 trial evaluating onvansertib, a PLK1 inhibitor, combined with standard chemotherapy and bevacizumab for first-line treatment of RAS-mutated metastatic colorectal cancer at the ASCO 2026 Annual Meeting in Chicago on June 2, 2026.

04/21/2026, 10:00 AMGlobeNewswire

Cardiff Oncology to Present Preclinical Data with Highly Specific PLK1 Inhibitor Onvansertib at the 2026 AACR Annual Meeting

Cardiff Oncology announced preclinical data showing its PLK1 inhibitor onvansertib enhanced antitumor activity of trastuzumab deruxtecan and reversed resistance in therapy-resistant HER2-low breast cancer models. The findings will be presented at the AACR Annual Meeting in April 2026. Onvansertib is currently in mid-stage clinical development for RAS-mutated metastatic colorectal cancer and other cancers.

03/19/2026, 7:00 AMGlobeNewswire

Cardiff Oncology to Present at the Piper Sandler 37th Annual Healthcare Conference

Cardiff Oncology will participate in the Piper Sandler 37th Annual Healthcare Conference, with CEO Mark Erlander presenting on December 2, 2025, discussing their PLK1 inhibition cancer therapies and lead asset onvansertib.

11/24/2025, 7:00 AMGlobeNewswire

KRAS Inhibitors Market to Witness Explosive Growth at a CAGR of 35% During the Forecast Period (2025–2034) Amid Expanding Therapeutic Landscape | DelveInsight

The KRAS inhibitors market is projected to grow at a 35% CAGR from 2025-2034, driven by rising cancer incidence and a robust pipeline of targeted therapies for KRAS mutations across multiple cancer types.

11/12/2025, 1:00 PMGlobeNewswire

Peers

Statistics

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Day Range
$1.35
$1.55
$1.40
1-Year Range
$1.40
$4.45
$1.40
Latest Close$1.40
Change
-$0.11 (-7.86%)
Volume2,501,782
Market Cap$129.9M
Shares Outstanding68.4M
P/E (TTM)-2.86
Diluted EPS (TTM)-$0.67
Enterprise Value$121.4M

Information as of 06/03/2026

Company Profile

$129.9M
Market Cap
-$44.8M
Net Income
Sector: Healthcare
Industry: Biotechnology
11055 Flintkote Avenue, San Diego, CA, United States, 92121
858 952 7570

Cardiff Oncology, Inc., a clinical-stage biotechnology company, develops novel therapies for the treatment of various cancers in the United States. Its lead drug candidate is Onvansertib, an oral and selective polo-like kinase 1 inhibitor for treating RAS-mutated metastatic colorectal cancer. The company also focuses on the clinical program in indications, such as investigator-initiated trials in metastatic pancreatic ductal adenocarcinoma, small cell lung cancer, metastatic triple negative breast cancer, and chronic myelomonocytic leukemia; CRDF-004, a Phase 2 open-label randomized multi-center clinical trial of onvansertib in combination with FOLFIRI and bevacizumab or FOLFOX and bevacizumab for the treatment of patients confirmed metastatic and unresectable colorectal cancer in patients with a KRAS or NRAS mutation; and TROV-054, a Phase 1b/2 single-arm clinical trial in KRAS-mutated metastatic colorectal cancer. The company was formerly known as Trovagene, Inc. and changed its name to Cardiff Oncology, Inc. in May 2012. Cardiff Oncology, Inc. was founded in 1999 and is headquartered in San Diego, California.

Key Executives

  • Tod Smeal
  • Josh Muntner
  • Roger Sidhu
  • Mani Mohindru
  • Elizabeth Anderson

Current Ownership Distribution

  • Institutions293.3M (66.93%)
  • Mutual Funds116.6M (26.61%)
  • Insiders28.3M (6.46%)
  • Other0 (0.00%)