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- $508.4MMarket Cap
- 81.93%1-Year Change
- BiotechnologyIndustry
MEIRAGTX (MGTX)
Key Performance
More- Earnings Score: 48
- Momentum Score: 89
- True Yield: N/A
- Financial Health Score: 92
Latest Research & News
Eli Lilly Partner MeiraGTx Regains Rights For Genetic Eye Disease Drug From Johnson & Johnson
MeiraGTx reacquired bota-vec, a treatment for X-linked retinitis pigmentosa (XLRP), from Johnson & Johnson for a $25 million upfront payment. The company raised $100 million through a share offering and plans to expedite regulatory filings for U.S. and EU approval with a potential 2027 launch. Three-year data from its xerostomia treatment showed durable benefits. Stock declined 15.8% on the announcement.
04/16/2026, 10:16 AM • Benzinga
MeiraGTx has entered into an asset purchase agreement with Johnson & Johnson to acquire all interests in botaretigene sparoparvovec (bota-vec) for treating X-linked retinitis pigmentosa. The company will pay $25 million upfront plus regulatory and commercial milestones, with royalties on global net sales. Phase 3 LUMEOS study data showed clinically meaningful improvements across multiple vision domains, with 45% of treated patients gaining >10 letters in low luminance visual acuity. MeiraGTx intends to file for regulatory approval in the U.S., EU, and Japan with a potential launch in 2027.
04/16/2026, 7:10 AM • Benzinga
Eli Lilly Expands Genetic Eye-Disease Focused Pipeline With MeiraGTx Gene Therapy Collaboration
Eli Lilly signed a strategic collaboration with MeiraGTx for ophthalmology gene therapy, granting worldwide exclusive rights to AAV-AIPL1 program for Leber congenital amaurosis 4, with an upfront payment of $75 million and potential milestone payments over $400 million.
11/10/2025, 9:11 AM • Benzinga
MeiraGTx Sales Jump 1,133 Percent
MeiraGTx reported Q2 2025 results with significant revenue growth but missed analyst estimates. The company advanced several gene therapy programs, secured key partnerships, and maintained strong manufacturing capabilities despite ongoing financial challenges.
08/14/2025, 8:31 AM • The Motley Fool
A comprehensive analysis reveals over 70 companies developing AAV gene therapies for hereditary retinal diseases, offering potential transformative treatments for vision restoration through advanced gene therapy techniques.
08/05/2025, 1:00 PM • GlobeNewswire
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MoreInformation as of 06/22/2026
Company Profile
MeiraGTx Holdings plc, a clinical-stage genetic medicines company, focusing on developing treatments for patients with serious diseases. The company develops various therapies for ocular diseases, including inherited retinal diseases and large degenerative ocular diseases; neurodegenerative diseases; and xerostomia. It is also develops AAV-AQP1 for radiation-induced grade 2/3 radiation-induced xerostomia, as well as for Sjogren's syndrome; AAV-GAD in Phase 2 trial for Parkinson's disease; AAV-RPE65 in Phase 2 trial for RPE65-associated retinal dystrophy; and AAV-CNGB3 and AAV-CNGA3, which are both in Phase ½ clinical trial for achromatopsia, as well as offers AAV-AIPL1 for Leber congenital amaurosis (LCA) 4. In addition, the company's products under preclinical development include AAV-RDH12 for retinol dehydrogenase 12 mutation-associated retinal dystrophy; AAV-BBS10 for Bardet-Biedl syndrome (BBS) due to BBS10 mutations; AAV-RetGC for LCA type 1; and AAV-UPF1 for amyotrophic lateral sclerosis, as well as programs for Alzheimer's disease, and wet and dry neovascular age related macular degeneration. Further, it provides riboswitch platform for the delivery of metabolic peptides; and cell therapies for oncology, autoimmune disease, and long term intractable pain. The company has collaborations with Johnson & Johnson Innovative Medicine for the research, development, and commercialization of gene therapies for the treatment of inherited retinal disease; and Hologen Limited for the research, development, manufacture, and commercialization of AAV-GAD investigational gene therapy for the treatment of Parkinson's disease, AAV-BDNF investigational gene therapy for genetic obesity disorders, and other genetic medicines to the central nervous system. MeiraGTx Holdings plc was founded in 2015 and is based in New York, New York.
Key Executives
- Alexandria Forbes
- Richard Brian Giroux
- Stuart Naylor
- Robert K. Zeldin
- Christine Elise Sheehy
Current Ownership Distribution
- Institutions803.7M (92.09%)
- Insiders34.9M (4.00%)
- Mutual Funds34.2M (3.91%)
- Other0 (0.00%)