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ORCHESTRA (OBIO)
NASDAQ
$3.84-$0.07 (-1.84%)
Price as of Jun 03, 2026 7:55 PM EDT- $234.1MMarket Cap
- 20.68%1-Year Change
- BiotechnologyIndustry
ORCHESTRA (OBIO)
$3.84-$0.07 (-1.84%)
Top Holders
Institutional
Mutual Funds
Holder | Ownership %
| Shares Held | Change (Shares, %) | Report Date |
|---|---|---|---|---|
RTW INVESTMENTS, LP | 13.87% | 8.3M | 0 (0.00%) | Mar 31, 2026 |
PERCEPTIVE ADVISORS LLC | 8.41% | 5.0M | -89,350 (-1.77%) | Mar 31, 2026 |
N/A | 3.68% | 2.2M | +2.2M (+100.00%) | Mar 31, 2026 |
BLACKROCK FUNDING, INC. /DE | 3.30% | 2.0M | +36,439 (+1.84%) | Dec 31, 2024 |
BLACKROCK INC. | 3.11% | 1.9M | +423,784 (+22.72%) | Jun 30, 2024 |
VANGUARD GROUP INC | 2.68% | 1.6M | +122,681 (+7.65%) | Dec 31, 2025 |
ALYESKA INVESTMENT GROUP, L.P. | 1.67% | 1.0M | 0 (0.00%) | Mar 31, 2026 |
Holder | Ownership %
| Shares Held | Change (Shares, %) | Report Date |
|---|---|---|---|---|
VANGUARD INDEX FUNDS | 3.60% | 2.2M | +820,464 (+38.08%) | Mar 31, 2026 |
FIDELITY CONCORD STREET TRUST | 0.64% | 385,433 | +32,755 (+8.50%) | Feb 28, 2026 |
FIDELITY SALEM STREET TRUST | 0.43% | 259,005 | 0 (0.00%) | Mar 31, 2026 |
T. Rowe Price Health Sciences Fund, Inc. | 0.43% | 258,756 | 0 (0.00%) | Mar 31, 2026 |
SCHWAB STRATEGIC TRUST | 0.37% | 224,313 | +45,081 (+20.10%) | Feb 28, 2026 |
Simplify Exchange Traded Funds | 0.37% | 219,387 | +219,387 (+100.00%) | Mar 31, 2026 |
BLACKROCK FUNDS | 0.35% | 210,594 | 0 (0.00%) | Mar 31, 2026 |
Current Ownership Distribution
- Institutions127.0M (74.80%)
- Mutual Funds28.3M (16.69%)
- Insiders14.5M (8.52%)
- Other0 (0.00%)
Insider Transactions
- 8.52% (14.5M)Current InsiderOwnership (%, shares)
- 6Number of InsiderBuying (last 12 months)
- $23.8MAmount of InsiderBuying (last 12 months)
- 2Number of InsiderSelling (last 12 months)
- $44.0MAmount of InsiderSelling (last 12 months)
Insider Name & Title | Type | Date
| Transaction Value | Shares | Share Price | Shares After Transactions |
|---|---|---|---|---|---|---|
Sherman Darren See Remarks | Sell | Jun 01, 2026 | $58,050.00 | 15,000 | $3.87 | 1.2M |
Sherman Darren See Remarks | In Kind | May 28, 2026 | $19,601.50 | 4,925 | $3.98 | 1.2M |
Taylor Andrew Lawrence Chief Financial Officer | In Kind | May 28, 2026 | $12,242.48 | 3,076 | $3.98 | 629,417 |
Fain Eric S | Buy | May 14, 2026 | $82,600.00 | 20,000 | $4.13 | 91,709 |
RTW INVESTMENTS, LP | In The Money | Apr 27, 2026 | $3.4M | 1.3M | $2.75 | 2.4M |
RTW INVESTMENTS, LP | In The Money | Apr 27, 2026 | $125.00 | 1.3M | $0.00 | 9.6M |
RTW INVESTMENTS, LP | Sell | Apr 27, 2026 | $132.16 | 32 | $4.13 | 9.6M |
Hochman David P See Remarks | In Kind | Mar 25, 2026 | $148,241.66 | 32,438 | $4.57 | 1.1M |
Aiello Joshua Principal Accounting Officer | In Kind | Mar 25, 2026 | $1,101.37 | 241 | $4.57 | 18,644 |
Sherman Darren See Remarks | In Kind | Mar 25, 2026 | $152,258.69 | 33,317 | $4.57 | 1.2M |
Hochman David P See Remarks | Buy | Mar 13, 2026 | $42,900.00 | 10,000 | $4.29 | 1.1M |
Hochman David P See Remarks | Award | Feb 12, 2026 | $0.00 | 504,000 | $0.00 | 1.1M |
Cleary Chris | In Kind | Feb 05, 2026 | $2,507.96 | 676 | $3.71 | 36,901 |
Sherman Darren See Remarks | Award | Jan 28, 2026 | $0.00 | 34,974 | $0.00 | 34,974 |
Sherman Darren See Remarks | In Kind | Jan 02, 2026 | $24,084.28 | 5,588 | $4.31 | 840,569 |
Aiello Joshua Principal Accounting Officer | In Kind | Jan 02, 2026 | $1,038.71 | 241 | $4.31 | 18,885 |
Taylor Andrew Lawrence Chief Financial Officer | In Kind | Jan 02, 2026 | $14,878.12 | 3,452 | $4.31 | 451,493 |
Sherman Darren See Remarks | In Kind | Nov 25, 2025 | $215,819.00 | 40,340 | $5.35 | 846,157 |
Hochman David P See Remarks | Buy | Nov 14, 2025 | $20,350.00 | 5,000 | $4.07 | 612,822 |
Hochman David P See Remarks | In Kind | Nov 13, 2025 | $13,722.94 | 3,283 | $4.18 | 607,822 |
Hochman David P See Remarks | In Kind | Nov 13, 2025 | $13,722.94 | 3,283 | $4.18 | 442,765 |
Hochman David P See Remarks | In Kind | Sep 17, 2025 | $99,273.30 | 40,355 | $2.46 | 611,105 |
Hochman David P See Remarks | In Kind | Sep 17, 2025 | $8,076.18 | 3,283 | $2.46 | 446,048 |
Aiello Joshua Principal Accounting Officer | In Kind | Sep 17, 2025 | $499.38 | 203 | $2.46 | 19,126 |
Sherman Darren See Remarks | In Kind | Sep 03, 2025 | $109,724.80 | 40,340 | $2.72 | 886,497 |
Taylor Andrew Lawrence Chief Financial Officer | Buy | Aug 25, 2025 | $5,100.00 | 2,000 | $2.55 | 482,788 |
Sherman Darren See Remarks | Buy | Aug 25, 2025 | $7,860.00 | 3,000 | $2.62 | 926,837 |
Fain Eric S | Buy | Aug 25, 2025 | $15,033.60 | 5,760 | $2.61 | 71,709 |
Aiello Joshua Principal Accounting Officer | Award | Aug 07, 2025 | $0.00 | 15,000 | $0.00 | 19,329 |
Pacitti David | Award | Aug 07, 2025 | $0.00 | 15,000 | $0.00 | 44,968 |