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ORCHESTRA (OBIO)
NASDAQ
$5.96-$0.39 (-6.14%)
Price as of Oct 02, 2026 4:15 PM EDT- $381.7MMarket Cap
- 136.94%1-Year Change
- BiotechnologyIndustry
ORCHESTRA (OBIO)
$5.96-$0.39 (-6.14%)
Top Holders
Institutional
Mutual Funds
Holder | Ownership %
| Shares Held | Change (Shares, %) | Report Date |
|---|---|---|---|---|
RTW INVESTMENTS, LP | 15.96% | 9.6M | +1.3M (+13.08%) | Jun 30, 2026 |
PERCEPTIVE ADVISORS LLC | 8.41% | 5.0M | 0 (0.00%) | Jun 30, 2026 |
BLACKROCK, INC. | 4.19% | 2.5M | +1.9M (+74.68%) | Jun 30, 2026 |
N/A | 3.68% | 2.2M | +2.2M (+100.00%) | Mar 31, 2026 |
VANGUARD CAPITAL MANAGEMENT LLC | 3.38% | 2.0M | -181,403 (-8.97%) | Jun 30, 2026 |
BLACKROCK FUNDING, INC. /DE | 3.30% | 2.0M | +36,439 (+1.84%) | Dec 31, 2024 |
BLACKROCK INC. | 3.11% | 1.9M | +423,784 (+22.72%) | Jun 30, 2024 |
Holder | Ownership %
| Shares Held | Change (Shares, %) | Report Date |
|---|---|---|---|---|
VANGUARD INDEX FUNDS | 3.29% | 2.0M | -186,026 (-9.45%) | Jun 30, 2026 |
iSHARES TRUST | 2.24% | 1.3M | 0 (0.00%) | Jul 31, 2026 |
FIDELITY SALEM STREET TRUST | 0.72% | 428,758 | +391,532 (+91.32%) | Jul 31, 2026 |
FIDELITY CONCORD STREET TRUST | 0.64% | 383,031 | 0 (0.00%) | Jul 31, 2026 |
T. Rowe Price Health Sciences Fund, Inc. | 0.43% | 258,756 | 0 (0.00%) | Jun 30, 2026 |
SCHWAB STRATEGIC TRUST | 0.37% | 221,958 | -2,355 (-1.06%) | May 31, 2026 |
Simplify Exchange Traded Funds | 0.37% | 219,387 | 0 (0.00%) | Jun 30, 2026 |
Current Ownership Distribution
- Institutions155.1M (74.80%)
- Mutual Funds37.9M (18.29%)
- Insiders14.3M (6.92%)
- Other0 (0.00%)
Insider Transactions
- 6.92% (14.3M)Current InsiderOwnership (%, shares)
- 2Number of InsiderBuying (last 12 months)
- $9.7MAmount of InsiderBuying (last 12 months)
- 1Number of InsiderSelling (last 12 months)
- $17.5MAmount of InsiderSelling (last 12 months)
Insider Name & Title | Type | Date
| Transaction Value | Shares | Share Price | Shares After Transactions |
|---|---|---|---|---|---|---|
Sherman Darren See Remarks | Sell | Oct 01, 2026 | $95,400.00 | 15,000 | $6.36 | 1.1M |
Hochman David P See Remarks | Buy | Sep 03, 2026 | $47,900.00 | 10,000 | $4.79 | 1.1M |
Sherman Darren See Remarks | Sell | Sep 01, 2026 | $74,100.00 | 15,000 | $4.94 | 1.1M |
Taylor Andrew Lawrence Chief Financial Officer | In Kind | Aug 26, 2026 | $16,179.76 | 3,076 | $5.26 | 589,989 |
Sherman Darren See Remarks | In Kind | Aug 26, 2026 | $25,905.50 | 4,925 | $5.26 | 1.1M |
Sherman Darren See Remarks | Buy | Aug 26, 2026 | $10,660.00 | 2,000 | $5.33 | 2,000 |
Pacitti David | In Kind | Aug 12, 2026 | $16,623.62 | 3,761 | $4.42 | 54,750 |
Cleary Chris | In Kind | Aug 12, 2026 | $18,731.96 | 4,238 | $4.42 | 29,153 |
Fain Eric S | In Kind | Aug 12, 2026 | $22,740.90 | 5,145 | $4.42 | 99,630 |
Sherman Darren See Remarks | Sell | Jul 01, 2026 | $64,050.00 | 15,000 | $4.27 | 1.2M |
Mack John Prosper | In Kind | Jun 24, 2026 | $0.00 | 3,510 | $0.00 | 71,429 |
Fain Eric S | In Kind | Jun 24, 2026 | $0.00 | 4,261 | $0.00 | 104,775 |
Yanchik Connealy Pamela | Award | Jun 23, 2026 | $0.00 | 21,277 | $0.00 | 21,277 |
Fain Eric S | Award | Jun 23, 2026 | $0.00 | 21,277 | $0.00 | 21,277 |
Mack John Prosper | Award | Jun 23, 2026 | $0.00 | 34,653 | $0.00 | 74,939 |
Fain Eric S | Award | Jun 23, 2026 | $0.00 | 17,327 | $0.00 | 109,036 |
Yanchik Connealy Pamela | Award | Jun 23, 2026 | $0.00 | 17,327 | $0.00 | 66,038 |
Hochman David P See Remarks | In Kind | Jun 10, 2026 | $13,197.66 | 3,283 | $4.02 | 1.1M |
Hochman David P See Remarks | In Kind | Jun 10, 2026 | $13,197.66 | 3,283 | $4.02 | 436,199 |
Sherman Darren See Remarks | In Kind | Mar 25, 2026 | $152,258.69 | 33,317 | $4.57 | 1.2M |
Hochman David P See Remarks | In Kind | Mar 25, 2026 | $148,241.66 | 32,438 | $4.57 | 1.1M |
Aiello Joshua Principal Accounting Officer | In Kind | Mar 25, 2026 | $1,101.37 | 241 | $4.57 | 18,644 |
Hochman David P See Remarks | Buy | Mar 13, 2026 | $42,900.00 | 10,000 | $4.29 | 1.1M |
Hochman David P See Remarks | Award | Feb 12, 2026 | $0.00 | 504,000 | $0.00 | 1.1M |
Cleary Chris | In Kind | Feb 05, 2026 | $2,507.96 | 676 | $3.71 | 36,901 |
Sherman Darren See Remarks | Award | Jan 28, 2026 | $0.00 | 34,974 | $0.00 | 34,974 |
Aiello Joshua Principal Accounting Officer | In Kind | Jan 02, 2026 | $1,038.71 | 241 | $4.31 | 18,885 |
Sherman Darren See Remarks | In Kind | Jan 02, 2026 | $24,084.28 | 5,588 | $4.31 | 840,569 |
Taylor Andrew Lawrence Chief Financial Officer | In Kind | Jan 02, 2026 | $14,878.12 | 3,452 | $4.31 | 451,493 |
Sherman Darren See Remarks | In Kind | Nov 25, 2025 | $215,819.00 | 40,340 | $5.35 | 846,157 |