Oncolytics Biotech® to Present Data at ASCO 2026 Reinforcing Pelareorep’s Potential Across Gastrointestinal Tumors

Oncolytics Biotech announced translational data from GOBLET and AWARE-1 trials demonstrating that pelareorep induces both innate and adaptive immune responses capable of controlling tumor growth. Data shows expansion of tumor-specific T cells and mutant KRAS-specific clones correlating with tumor regression in pancreatic cancer, and increased immune gene expression in breast cancer. The company also reported durable responses in colorectal cancer and alignment with FDA on a planned pivotal anal cancer study.

05/22/2026, 9:00 AM • GlobeNewswire

"Cold" Solid Tumors Become the Proving Ground for a New Generation of Engager and Immune-Priming Therapies

A new generation of immuno-oncology therapies targeting historically immunotherapy-resistant solid tumors like prostate and pancreatic cancer is advancing rapidly through clinical trials in 2026. Four distinct mechanistic approaches—including NK cell engagers, oncolytic virus immune-primers, and tumor microenvironment-conditional antibodies—are being developed by multiple biotech companies, with over $1.7 billion in dealmaking activity. GT Biopharma's GTB-5550 NK cell engager and Vir Biotechnology's VIR-5500 PSMA-targeted T-cell engager represent leading programs in this emerging therapeutic landscape.

05/14/2026, 10:55 AM • GlobeNewswire

The Patent Cliff is Coming, Driving Smart Money Towards Precision Oncology

Institutional investors are rotating capital toward clinical-stage biotech companies focused on precision medicine, with the oncology precision medicine market projected to reach $303 billion by 2035. Five companies—Oncolytics Biotech, OS Therapies, Sensei Biotherapeutics, Atossa Therapeutics, and Tango Therapeutics—are advancing promising cancer treatments with strong clinical data and FDA support, positioning themselves for potential M&A activity as major pharma companies seek differentiated assets.

03/19/2026, 11:00 AM • GlobeNewswire

New Treatment Modalities Are Reaching Cancers That Resisted Everything Else

Several biotech companies are advancing novel cancer treatments through clinical development. Oncolytics Biotech received FDA Fast Track Designation for pelareorep in KRAS-mutant colorectal cancer, showing doubled survival benefits. Novocure gained FDA approval for Optune Pax for pancreatic cancer. Perspective Therapeutics presented positive interim data for its radiopharmaceutical VMT-α-NET. ImmunityBio launched a Phase 2 trial for its CAR-NK cell therapy combined with IL-15 superagonist. Nuvation Bio expanded its Phase 3 trial for safusidenib in IDH1-mutant glioma.

02/17/2026, 11:17 AM • Benzinga

$207B Market Shift: The Race for Fast Track Approval in Oncology

The FDA has accelerated oncology drug approvals with over 50 approvals in 2025 and increased expedited designations in 2026. Multiple biotech companies are advancing cancer treatments through Fast Track and Breakthrough Therapy designations, targeting high-unmet-need solid tumors. Key developments include Oncolytics' pelareorep showing significant survival benefits in colorectal cancer, Relay's zovegalisib receiving Breakthrough designation for breast cancer, MAIA's ateganosine advancing in lung cancer, Zai Lab's AUGTYRO approval in China, and Arrivent's firmonertinib entering pivotal Phase 3 trials for NSCLC.

02/05/2026, 9:35 AM • Benzinga

Oncolytic Virotherapy Market - Global Industry Size, Share, Trends, Opportunity, and Forecast, 2021-2031

The global oncolytic virotherapy market is projected to grow from USD 49.73 million in 2025 to USD 153.31 million by 2031, with a CAGR of 20.64%. Growth is driven by rising cancer incidence, advances in genetic engineering, and synergistic combination therapies with checkpoint inhibitors. However, host immune system challenges and premature viral clearance remain significant obstacles to market expansion.

01/23/2026, 5:52 AM • GlobeNewswire

Precision Killers: Why Big Pharma is Betting Billions to Beat a $170B Patent Cliff

The precision oncology market is projected to grow from $110 billion to $225.65 billion by 2032, driven by Big Pharma's race to acquire registration-ready assets ahead of a $170 billion patent cliff through 2030. Several biotech companies are advancing promising clinical programs: Oncolytics Biotech strengthened its leadership team for pelareorep development in gastrointestinal cancers; Nurix is executing pivotal studies for its BTK degrader bexobrutideg in chronic lymphocytic leukemia; Erasca reported early clinical data for its pan-RAS molecular glue ERAS-0015; Foghorn raised $50 million for its SMARCA4-targeting program; and ORIC presented strong Phase 1b data for rinzimetostat in prostate cancer.

01/14/2026, 10:52 AM • Benzinga

Fast-Tracking the $537B Cancer Cure: How Accelerated Approvals Reshaping Oncology in 2026

The oncology landscape is experiencing rapid regulatory advancement as precision medicine and genomics expand significantly. Multiple biotech companies are advancing cancer therapies toward accelerated FDA approvals in 2026, with the precision medicine market projected to grow from $138.67 billion in 2026 to $537.17 billion by 2035. Key developments include Oncolytics' pelareorep showing strong response rates in anal cancer, CG Oncology's Phase 3 trial ahead of schedule, Zentalis advancing azenosertib in ovarian cancer, ArriVent initiating a pivotal Phase 3 study for firmonertinib, and PDS Biotechnology gaining FDA alignment on trial endpoints.

01/12/2026, 10:35 AM • Benzinga

Immunotherapy Breakthroughs Turn Cold GI Tumors Hot as Market Tops $443B

Emerging immunotherapy technologies are transforming treatment for gastrointestinal cancers, with companies developing novel combination strategies to activate immune responses in historically resistant tumors. The global cancer immunotherapy market is projected to reach $443.17 billion by 2030.

12/16/2025, 1:17 PM • Benzinga

THE VISIBILITY INDEX: 5 Companies Solving the Invisible Crisis

The market is shifting focus towards technologies that can detect previously invisible threats across healthcare, resource exploration, and diagnostics, with several companies developing innovative solutions for cardiac care, diabetes treatment, cancer therapy, and mineral exploration.

12/15/2025, 10:54 AM • GlobeNewswire

THE EFFICIENCY PARADOX: 5 Market Anomalies Trading Below Reality

Market intelligence report highlighting five undervalued companies across biotech, AI, defense, gold exploration, and medical technology sectors, suggesting significant potential for valuation growth due to technological innovations and strategic positioning.

12/06/2025, 1:51 PM • GlobeNewswire

Oncolytics Biotech® Announces Update for Potential First-Line Pancreatic Cancer Registration Study

Oncolytics Biotech is planning a three-arm clinical trial for pancreatic cancer treatment, involving pelareorep in combination with chemotherapy and checkpoint inhibitors, with a planned FDA meeting in November 2025 to discuss study details.

09/29/2025, 8:30 AM • Benzinga

Cancer Immunotherapy Surge Drives $258B Market as FDA Accelerates Approvals

The cancer immunotherapy market is projected to reach $258.22 billion by 2031, driven by breakthrough treatments and FDA fast-track approvals. Multiple companies are developing innovative immunotherapies targeting various cancer types with promising clinical trial results.

09/16/2025, 12:29 PM • Benzinga

FDA Tightens Survival Standards as Cancer Drug Pipeline Hits $866B Market Milestone

The FDA is tightening survival standards in cancer research, with private investments helping to fill public funding gaps. Several biotech companies are advancing innovative immunotherapies, with Oncolytics Biotech showing promising results in pancreatic cancer treatment.

08/28/2025, 10:44 AM • Benzinga

Oncolytics Biotech® Reports Second Quarter Financial Results and Details Clinical Program Plans for Pelareorep

Oncolytics Biotech reported Q2 2025 financial results, highlighting promising clinical data for pelareorep in pancreatic cancer and plans to pursue a registration-enabling pivotal study with potential FDA approval.

08/08/2025, 9:05 AM • Benzinga