• $1.1B
    Market Cap
  • 12.60%
    1-Year Change
  • Diagnostics & Research
    Industry

Key Performance

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  • Earnings Score: 21
  • Momentum Score: 49
  • True Yield: N/A
  • Financial Health Score: 44
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Latest Research & News

OPKO Health to Report Fourth Quarter 2025 Financial Results on February 26

OPKO Health will report its financial results for Q4 and full year 2025 on February 26, 2026, followed by a conference call. The company has also expanded its partnership with Entera Bio to advance an oral long-acting PTH tablet for hypoparathyroidism treatment, marking the third successful program combining Entera's N-Tab platform with OPKO's protein chemistry capabilities.

02/12/2026, 8:00 AM • GlobeNewswire

OPKO Health and Entera Bio Expand Partnership to Advance First-in-Class Oral Long Acting PTH Tablet for Patients with Hypoparathyroidism

OPKO Health and Entera Bio have expanded their collaboration to develop the first oral long-acting PTH analog for hypoparathyroidism treatment, aiming to file an IND application in late 2026. The companies will maintain equal 50/50 ownership and cost-sharing for this program. Additionally, they are advancing oral oxyntomodulin (dual GLP-1/glucagon analog) with Phase 1 injectable data expected by end of 2026. Steve Rubin from OPKO has joined Entera's board.

02/04/2026, 8:00 AM • GlobeNewswire

Entera Bio to Participate in the 8th Annual Evercore ISI Healthcare Conference

Entera Bio's CEO will participate in the Evercore ISI Healthcare Conference, highlighting the company's progress in developing oral peptide therapies for conditions like osteoporosis and hypoparathyroidism.

11/18/2025, 8:00 AM • GlobeNewswire

NextPlat Issues CEO Shareholder Update Letter

NextPlat Corp provides an update on its strategic progress across healthcare services, communications, and e-commerce channels, highlighting cost reduction efforts, new contracts, and technology investments aimed at driving growth and profitability.

10/08/2025, 8:02 AM • Benzinga

Entera Bio Beats Q2 EPS Estimates

Entera Bio reported better-than-expected Q2 2025 earnings with a GAAP EPS of $0.06, secured FDA regulatory concurrence for EB613's Phase 3 trial, and maintained a strong cash position of $18.8 million to support operations through mid-Q3 2026.

08/08/2025, 5:17 PM • The Motley Fool

NextPlat Issues Interim CEO Update Shareholder Letter

NextPlat's interim CEO David Phipps outlined strategic plans to improve healthcare and e-commerce divisions, focusing on operational efficiency, cost reduction, and exploring growth opportunities following the unexpected passing of former CEO Charles M. Fernandez.

06/30/2025, 8:01 AM • Benzinga

OPKO Health to Participate in the 3rd Annual Piper Sandler Virtual Obesity Symposium

OPKO Health, Inc. and Entera Bio Ltd. announced that OPKO's ModeX Therapeutics division has formed a Scientific Advisory Board with leaders in immunology and oncology drug development. Additionally, OPKO and Entera's first-in-class dual GLP-1/Glucagon tablet candidate for obesity and metabolic disorders has been selected for presentation at the ENDO 2025 Annual Meeting.

06/25/2025, 11:00 AM • GlobeNewswire

Peers

Statistics

More
Day Range
$1.36
$1.47
$1.43
1-Year Range
$1.10
$1.58
$1.43
Latest Close$1.43
Change
+$0.01 (+0.70%)
Volume3,786,854
Market Cap$1.1B
Shares Outstanding755.1M
P/E (TTM)-5.19
Diluted EPS (TTM)-$0.28
Enterprise Value$821.2M

Information as of 06/22/2026

Company Profile

OPKO HEALTH INC
https://www.opko.com
$1.1B
Market Cap
-$212.9M
Net Income
Sector: Healthcare
Industry: Diagnostics & Research
4400 Biscayne Boulevard, Miami, FL, United States, 33137
305 575 4100

OPKO Health, Inc. operates as a healthcare company, in the United States, Ireland, Chile, Spain, Israel, Mexico, and internationally. The company operates in two segments, Pharmaceutical and Diagnostics. The Pharmaceutical segment develops MDX2001, a tetra-specific antibody targeting several types of solid tumors in Phase 1 clinical trials; MDX2003, a tetra-specific antibody targeting two antigens for hematological tumors in Phase 1 clinical trials; and MDX2004, a trispecific immune modulator to rebuild and sustain the patient's own immune system. This segment also engages in the development of Epstein Barr Virus vaccine; Rayaldee, a patented extended-release product for oral administration containing 30 mcg of a prohormone; OPK-88006 oral and injectable product to regulate blood glucose and reduce body weight; NGENLA, recombinant human growth hormone product developed for the long-term treatment of pediatric patients with growth hormone deficiency. The Diagnostics segment offers laboratory testing services, such as detection, diagnosis, evaluation, monitoring, and treatment of diseases, as well as esoteric testing, molecular diagnostics, anatomical pathology, genetics, women's health, and correctional healthcare under the BioReference brand; and 4Kscore test. OPKO Health, Inc. was founded in 2006 and is headquartered in Miami, Florida.

Key Executives

  • Phillip Frost
  • Elias Adam Zerhouni
  • Jane H. Hsiao
  • Steven D. Rubin
  • Adam E. Logal

Current Ownership Distribution

  • Institutions3.4B (72.44%)
  • Mutual Funds882.1M (18.70%)
  • Insiders418.3M (8.87%)
  • Other0 (0.00%)