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- $164.8MMarket Cap
- -4.23%1-Year Change
- BiotechnologyIndustry
TIZIANA LIFE SCI (TLSA)
Key Performance
More- Earnings Score: N/A
- Momentum Score: 32
- True Yield: N/A
- Financial Health Score: N/A
Latest Research & News
Tiziana Fully Enrolls its Phase 2 Placebo Controlled Multiple Sclerosis Trial
Tiziana Life Sciences announced completion of patient enrollment in its Phase 2a randomized, double-blind, placebo-controlled trial (INFORM-MS) evaluating intranasal foralumab in 48 patients with non-active Secondary Progressive Multiple Sclerosis. Topline data is expected in late Q3 2026 and will be presented at the ACTRIMS/ECTRIMS meeting in October 2026. The trial includes a six-month open-label extension phase to assess long-term safety and sustained benefit.
05/21/2026, 11:00 AM • GlobeNewswire
Tiziana Life Sciences announced positive preclinical data published on bioRxiv showing that intranasal foralumab, an anti-CD3 monoclonal antibody, significantly reduces neuroinflammation and improves cognitive function in a Long COVID mouse model. The study, conducted by researchers from Yale University and Harvard Medical School, demonstrated that the treatment increases regulatory T cells in the brain, restores neurogenesis, and rescues cognitive deficits. The company is advancing foralumab through clinical trials for multiple neurological conditions including multiple sclerosis, Alzheimer's disease, and ALS.
04/16/2026, 7:00 AM • GlobeNewswire
Tiziana Life Sciences (NASDAQ: TLSA) closed an oversubscribed $8.8 million registered direct offering of 7.04 million ordinary shares at $1.25 per share, with warrants providing up to $10.56 million in additional potential proceeds. The offering was led by CEO Ivor Elrifi and Executive Chairman Gabriele Cerrone. Proceeds will fund Phase 2 clinical trials for intranasal foralumab in na-SPMS and MSA patients.
01/16/2026, 2:45 PM • Benzinga
Tiziana Life Sciences closed an oversubscribed $8.8 million registered direct offering of 7.04 million ordinary shares at $1.25 per share, with warrants providing up to $10.56 million in additional potential proceeds. The funding will support completion of Phase 2 clinical trials for intranasal foralumab in na-SPMS and MSA patients. CEO Ivor Elrifi and Executive Chairman Gabriele Cerrone made significant purchases, demonstrating insider confidence.
01/16/2026, 2:45 PM • GlobeNewswire
Tiziana Life Sciences to Dose First Patient in Phase 2 Alzheimer’s Trial
Tiziana Life Sciences is launching a Phase 2 clinical trial for intranasal foralumab to treat early Alzheimer's disease, targeting neuroinflammation in combination with existing anti-amyloid therapies like Leqembi.
12/12/2025, 2:10 PM • GlobeNewswire
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MoreInformation as of 06/02/2026
Company Profile
Tiziana Life Sciences Ltd, a biotechnology company, engages in the development of transformative therapies for neurodegenerative and lung diseases in the United States. The company's lead product candidate in immunology is Foralumab (TZLS-401), a human anti-CD3 monoclonal antibody (mAb) for use in the treatment of Crohn's, graft versus host, ulcerative colitis, multiple sclerosis, type-1 diabetes, inflammatory bowel, psoriasis, and rheumatoid arthritis diseases. It is also developing TZLS-501, a fully human mAb targeting the IL-6 receptor for use in the treatment of inflammatory and oncology indications. Tiziana Life Sciences Ltd was incorporated in 1998 and is headquartered in London, the United Kingdom.
Key Executives
- Ivor R. Elrifi
- Gabriele Marco Antonio Cerrone
- Richard K. Kim
- William Edward Tente
- Keeren Shah
Current Ownership Distribution
- Insiders44.7M (44.96%)
- Institutions43.4M (43.71%)
- Mutual Funds11.3M (11.33%)
- Other0 (0.00%)