• $625.6M
    Market Cap
  • -25.22%
    1-Year Change
  • Biotechnology
    Industry

Key Performance

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  • Earnings Score: N/A
  • Momentum Score: 45
  • True Yield: N/A
  • Financial Health Score: N/A
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Latest Research & News

Gyre Therapeutics Completes Acquisition of Cullgen to Create U.S.- and China-based Fully Integrated Biopharmaceutical Company

Gyre Therapeutics has completed its all-stock acquisition of Cullgen Inc. for approximately $300 million, creating a fully integrated biopharmaceutical company with U.S. and China operations. The combined entity will have a commercial-stage product (ETUARY® for lung fibrosis) and a robust pipeline focused on fibrosis and inflammatory diseases, including the lead candidate F351 for liver fibrosis. Dr. Ying Luo, former CEO of Cullgen, becomes President and CEO of the combined company.

05/04/2026, 8:47 AM • Benzinga

Gyre Therapeutics Reports Fourth Quarter and Full Year 2025 Financial Results and Provides Business Update

Gyre Therapeutics reported full-year 2025 revenue of $116.6 million, up 10% year-over-year, within guidance. The company achieved alignment with China's CDE on conditional approval pathway for Hydronidone with NDA submission expected in H1 2026. Gyre completed enrollment in a Phase 3 pirfenidone pneumoconiosis trial and announced an agreement to acquire Cullgen for approximately $300 million to expand its targeted protein degradation platform. However, 2026 revenue guidance of $100.5-$111.0 million represents a 4.8-13.8% decline, reflecting a transition period prioritizing regulatory activities.

03/12/2026, 6:00 AM • GlobeNewswire

Gyre Therapeutics Reports Third Quarter 2025 and Year-to-Date Financial Results and Provides Business Update

Gyre Therapeutics reported Q3 2025 net income of $5.9 million, with quarterly revenue of $30.6 million, up 20% year-over-year. The company revised full-year revenue guidance to $115-118 million due to delayed product rollouts and procurement uncertainties.

11/07/2025, 6:00 AM • GlobeNewswire

Gyre Therapeutics to Present Results from Positive Phase 3 Clinical Trial Evaluating Hydronidone for the Treatment of Liver Fibrosis in Chronic Hepatitis B at AASLD—The Liver Meeting® 2025

Gyre Therapeutics will present positive Phase 3 clinical trial results for Hydronidone, a novel anti-fibrotic agent targeting liver fibrosis in chronic hepatitis B, at AASLD's The Liver Meeting® 2025 in Washington D.C.

10/14/2025, 7:00 AM • GlobeNewswire

Gyre Therapeutics Announces the Appointment of Dan Weng, M.D., to Board of Directors

Gyre Therapeutics announced the appointment of Dr. Dan Weng to its Board of Directors, bringing nearly four decades of clinical trial management experience. The company is focused on developing fibrosis treatments and has a prominent product in the Chinese market.

08/22/2025, 7:00 AM • GlobeNewswire

Peers

Statistics

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Day Range
$5.80
$6.00
$5.86
1-Year Range
$5.56
$8.76
$5.86
Latest Close$5.86
Change
-$0.04 (-0.68%)
Volume66,577
Market Cap$625.6M
Shares Outstanding106.0M
P/E (TTM)-31.94
Diluted EPS (TTM)-$0.18
Enterprise Value$582.3M

Information as of 10/22/2026

Company Profile

GYRE THERAPEUTICS INC
https://www.gyretx.com
$625.6M
Market Cap
-$18.5M
Net Income
Sector: Healthcare
Industry: Biotechnology
12730 High Bluff Drive, San Diego, CA, United States, 92130
858-284-0115

Gyre Therapeutics, Inc., a pharmaceutical company, engages in the development and commercialization of small-molecule, anti-inflammatory, and anti-fibrotic drugs targeting organ fibrosis. The company offers ETUARY (Pirfenidone), an anti-fibrotic drug approved for the treatment of idiopathic pulmonary fibrosis; and under Phase 3 trials for the treatment of pneumoconiosis. It is also involved in the development of F351 (Hydronidone), a structural derivative of ETUARY under Phase 3 trials for the treatment of chronic hepatitis B (CHB)-associated liver fibrosis; and completed Phase 1 trials for the treatment of liver fibrosis associated with metabolic dysfunction-associated steatohepatitis. In addition, the company develops F573, which is in Phase 2 clinical trials for the treatment of acute/acute-on-chronic liver failure. Further, its preclinical products include F230 for the treatment of pulmonary arterial hypertension; and F528 to treat chronic obstructive pulmonary disease. Gyre Therapeutics, Inc. was founded in 2002 and is headquartered in San Diego, California. Gyre Therapeutics, Inc. operates as a subsidiary of GNI USA, Inc.

Key Executives

  • Weiguo Ye
  • Ruoyu Chen
  • Ying Luo
  • Thomas W. Eastling
  • Seth Goldblum

Current Ownership Distribution

  • Other59.6M (56.19%)
  • Institutions27.2M (25.67%)
  • Mutual Funds14.0M (13.21%)
  • Insiders5.2M (4.92%)