IOVA
IOVANCE BTHRPTCS (IOVA)
NASDAQ
$4.53+$0.47 (+11.58%)
Price as of Jun 23, 2026 7:59 PM EDT
  • $1.8B
    Market Cap
  • 119.46%
    1-Year Change
  • Biotechnology
    Industry

Key Performance

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  • Earnings Score: 24
  • Momentum Score: 27
  • True Yield: N/A
  • Financial Health Score: 96
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Latest Research & News

Iovance Biotherapeutics Reports Inducement Grants under NASDAQ Listing Rule 5635(c)(4)

Iovance Biotherapeutics approved the grant of inducement stock options covering 140,860 shares to 27 new non-executive employees on June 18, 2026, with an exercise price of $3.91 per share. The options vest over three years under the company's Amended and Restated 2021 Inducement Plan.

06/19/2026, 5:15 PMGlobeNewswire

Iovance Biotherapeutics Reports Inducement Grants under NASDAQ Listing Rule 5635(c)(4)

Iovance Biotherapeutics approved the grant of inducement stock options covering 93,340 shares to thirteen new non-executive employees on May 21, 2026, with an exercise price of $3.70 per share and a three-year vesting schedule.

05/22/2026, 5:15 PMGlobeNewswire

This Beaten-Down Growth Stock Could Soar 165%, According to Wall Street

Iovance Biotherapeutics (IOVA) has surged 34% in 2026 but lost 90% over five years. Wall Street analysts project a 165% upside to $9, driven by strong revenue growth (61% YoY) from its melanoma drug Amtagvi and potential expansion into lung cancer. However, the analyst remains skeptical, citing manufacturing complexity, high costs, and regulatory hurdles that could prevent the stock from reaching the $9 target within 12 months.

05/02/2026, 2:30 AMThe Motley Fool

Is This Biotech Stock the Best Chance to Make a Fortune in Healthcare?

Iovance Biotherapeutics' oncology drug Amtagvi is generating strong sales growth and expanding globally, with potential to exceed $1 billion annually by 2030. However, the company faces significant risks including high manufacturing costs, complex cell therapy administration, and regulatory uncertainties. The stock is recommended as a small initial position due to its high-risk, high-reward profile.

04/10/2026, 12:30 PMThe Motley Fool

Proleukin Market Research Report 2026-2035: Epidemiology, Pipeline Analysis, Industry Insights and More

The Proleukin market is projected to grow from $1.24 million in 2025 to $1.68 million by 2030, with a CAGR of 6.1%. Growth drivers include rising cancer prevalence, increased cystic fibrosis diagnoses, enhanced R&D investments, and the drug's approval for respiratory and oncology applications. Iovance Biotherapeutics acquired Proleukin in May 2023, strengthening its immunotherapy platform. North America currently leads the market, while Asia-Pacific is expected to be the fastest-growing region.

04/01/2026, 4:43 AMGlobeNewswire

The $578 Billion Regenerative Medicine Market Has a Manufacturing Problem. One Company Just Solved the First Step

The regenerative medicine market, projected to reach $578 billion by 2033, faces a critical manufacturing challenge in scaling cell and gene therapies. Several companies are addressing this bottleneck through different approaches: Prime Medicine with prime editing technology, Madrigal Pharmaceuticals with sustained therapeutic results, Iovance Biotherapeutics with FDA-approved TIL therapy, Denali Therapeutics with protein engineering, and Avaí Bio with a Master Cell Bank for encapsulated cell products that enable off-the-shelf manufacturing.

03/31/2026, 8:49 PMBenzinga

Iovance Biotherapeutics: The High‑Risk Cancer Stock I Think Could Change a Portfolio by 2036

Iovance Biotherapeutics is a high-risk biotech penny stock developing Amtagvi, a personalized cancer treatment approved for melanoma. The company showed strong 60.6% revenue growth in fiscal 2025 and is pursuing label expansions and international approvals. However, significant challenges including complex manufacturing processes, regulatory hurdles, and profitability concerns make this a speculative investment that could soar or crash over the next decade.

03/05/2026, 5:27 PMThe Motley Fool

1 Nearly Unknown Biotech Stock Set To Go Parabolic If Its Pipeline Hits

Iovance Biotherapeutics (IOVA), a biotech company with a market cap of $1.1B, recently won approval for lifileucel (Amtagvi), a tumor infiltrating lymphocyte treatment for melanoma. The drug is generating revenue growth with a 13% quarterly increase to $68 million, and real-world data shows a 52% objective response rate, exceeding clinical trial results. The company is studying lifileucel across multiple cancer indications, with several phase 2 trials underway. Trading at under $3 per share, the stock could see significant upside if the pipeline succeeds.

02/23/2026, 3:15 AMThe Motley Fool

Iovance Biotherapeutics Reports Inducement Grants under NASDAQ Listing Rule 5635(c)(4)

Iovance Biotherapeutics approved the grant of inducement stock options covering 3,600 shares to two new non-executive employees on February 19, 2026. The options have an exercise price of $2.85 per share and vest over three years under the company's Amended and Restated 2021 Inducement Plan.

02/20/2026, 5:15 PMGlobeNewswire

Stock Market Today, Feb. 18: ImmunityBio Soars After EU Approves ANKTIVA for Bladder Cancer

ImmunityBio stock surged 41.36% on Feb. 18, 2026, after the European Commission granted conditional marketing authorization for its Anktiva immunotherapy to treat bladder cancer. The approval expands access to over 30 new countries and positions the drug for accelerated sales growth. Despite the positive news, the stock remains volatile and heavily dependent on Anktiva's continued success.

02/18/2026, 5:17 PMThe Motley Fool

Best-in-Class Real-World Data Support Early Amtagvi® Treatment in Advanced Melanoma

Iovance Biotherapeutics announced real-world clinical data demonstrating a 44% objective response rate for Amtagvi (lifileucel) in previously treated advanced melanoma patients, exceeding the 31% rate from the original clinical trial. The therapy showed higher efficacy (52% ORR) when administered earlier in treatment. Amtagvi is the first FDA-approved one-time T cell therapy for solid tumors and the only approved treatment for advanced melanoma patients who have failed anti-PD-1 and targeted therapies.

02/05/2026, 5:15 PMGlobeNewswire

Autologous Cell Therapy Market Size to Reach US$ 44.55 Billion by 2033 | Astute Analytica

The global autologous cell therapy market, valued at $10.12 billion in 2024, is projected to grow to $44.55 billion by 2033 at a CAGR of 17.90%. Growth is driven by rising demand for personalized, patient-derived treatments for chronic diseases including cancer, cardiovascular disorders, and neurodegenerative conditions. North America leads the market with over 44% share, supported by a robust clinical trial ecosystem and regulatory frameworks like the FDA's RMAT designation.

01/27/2026, 1:43 PMGlobeNewswire

Iovance Biotherapeutics Reports Inducement Grants under NASDAQ Listing Rule 5635(c)(4)

Iovance Biotherapeutics announced the grant of inducement stock options covering 43,150 shares to four new non-executive employees on December 18, 2025, with an exercise price of $2.46 per share. The options vest over three years with one-third vesting on the first anniversary and remaining shares vesting quarterly over the following two years.

12/19/2025, 5:15 PMGlobeNewswire

2 Stocks That Could Soar by 52% and 282%, According to Wall Street

The article analyzes two biotech stocks, CRISPR Therapeutics and Iovance Biotherapeutics, discussing their potential growth, current market positions, and future prospects in gene-editing and cancer treatment therapies.

12/07/2025, 9:25 AMThe Motley Fool

Iovance Biotherapeutics Reports Inducement Grants under NASDAQ Listing Rule 5635(c)(4)

Iovance Biotherapeutics granted stock options covering 62,790 shares to nine new non-executive employees under its Inducement Plan, with options vesting over a three-year period.

10/17/2025, 5:15 PMGlobeNewswire

Peers

Statistics

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Day Range
$3.91
$4.20
$4.06
1-Year Range
$1.69
$5.41
$4.06
Latest Close$4.06
Change
+$0.15 (+3.69%)
Volume11,624,401
Market Cap$1.8B
Shares Outstanding446.5M
P/E (TTM)-0.004
Diluted EPS (TTM)-$928.75
Enterprise Value$1.6B

Information as of 06/22/2026

Company Profile

IOVANCE BIOTHERAPEUTICS INC
IOVANCE BIOTHERAPEUTICS INC
https://www.iovance.com
$1.8B
Market Cap
-$353.9M
Net Income
Sector: Healthcare
Industry: Biotechnology
825 Industrial Road, San Carlos, CA, United States, 94070
650 260 7120

Iovance Biotherapeutics, Inc., a commercial-stage biopharmaceutical company, develops and commercializes cell therapies using autologous tumor infiltrating lymphocyte for the treatment of metastatic melanoma and other solid tumor cancers in the United States and internationally. The company offers Amtagvi, an individualized T cell therapy for solid tumor cancer and for the treatment of adult patients with previously treated advanced, or unresectable or metastatic melanomal; and Proleukin, an interleukin-2 product for the treatment of patients with metastatic melanoma and metastatic renal cell carcinoma. It also develops lifileucel for the treatment of melanoma, cervical cancer, non-small cell lung cancer (NSCLC), endometrial cancer, and head and neck squamous cell carcinoma (HNSCC); LN-145-S1 to treat melanoma and HNSCC; LN-145 Gen 3 and core biopsy for the treatment of NSCLC; LN-145 Gen 3 to treat melanoma and HNSCC; IOV-2001 to treat chronic lymphocytic leukemia and small lymphocytic lymphoma; IOV-4001 for the treatment of melanoma and NSCLC; and IOV-3001 for use in the TIL therapy treatment regimen. The company has collaborations and licensing agreements with National Institutes of Health; the National Cancer Institute; Cellectis S.A.; Novartis Pharma AG; and Boehringer Ingelheim Biopharmaceuticals GmbH. The company was formerly known as Lion Biotechnologies, Inc. and changed its name to Iovance Biotherapeutics, Inc. in June 2017. Iovance Biotherapeutics, Inc. was incorporated in 2007 and is headquartered in San Carlos, California.

Key Executives

  • Frederick G. Vogt
  • Raj K. Puri
  • Daniel G. Kirby
  • Friedrich Graf Finckenstein
  • Igor Bilinsky

Current Ownership Distribution

  • Institutions3.8B (78.84%)
  • Mutual Funds963.4M (20.08%)
  • Insiders52.0M (1.08%)
  • Other0 (0.00%)