PRLD
PRELUDE THERAP (PRLD)
NASDAQ
$3.66+$0.16 (+4.57%)
Price as of Jun 03, 2026 7:01 PM EDT
  • $254.5M
    Market Cap
  • 274.21%
    1-Year Change
  • Biotechnology
    Industry

Key Performance

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  • Earnings Score: N/A
  • Momentum Score: 61
  • True Yield: N/A
  • Financial Health Score: N/A
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Latest Research & News

Prelude Therapeutics Presents Preclinical Data from Development Candidate, PRT13722, a First-in-Class, Orally Bioavailable, Potent and Highly Selective KAT6A Degrader at American Association for Cancer Research (AACR) Annual Meeting 2026

Prelude Therapeutics announced preclinical data for PRT13722, a first-in-class oral KAT6A degrader showing complete tumor regressions in HR+/HER2- breast cancer models with improved hematological safety compared to existing approaches. The company remains on track to file an IND application by mid-2026 and initiate clinical trials in the second half of 2026.

04/20/2026, 6:00 AM • GlobeNewswire

Prelude Therapeutics Presents Data at the 2025 ASH Annual Meeting from its Myeloproliferative Neoplasm (MPN) Programs

Prelude Therapeutics presented preclinical data on two promising therapeutic approaches for myeloproliferative neoplasms (MPNs): a JAK2V617F-selective JH2 inhibitor (PRT12396) and a mutant calreticulin targeted degrader antibody conjugate, demonstrating potential disease-modifying capabilities.

12/06/2025, 11:00 AM • GlobeNewswire

Prelude Cuts Q2 Losses and Costs 13%

Prelude Therapeutics reported a Q2 2025 net loss of $31.2 million, reduced operating expenses, and focused on its oral SMARCA2 degrader program while maintaining cash reserves to fund operations into Q2 2026.

08/14/2025, 7:23 AM • The Motley Fool

Peers

Statistics

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Day Range
$3.47
$3.76
$3.50
1-Year Range
$0.78
$5.52
$3.50
Latest Close$3.50
Change
-$0.32 (-9.14%)
Volume384,979
Market Cap$254.5M
Shares Outstanding64.9M
P/E (TTM)-3.96
Diluted EPS (TTM)-$0.99
Enterprise Value$232.7M

Information as of 06/02/2026

Company Profile

PRELUDE THERAPEUTICS INC
PRELUDE THERAPEUTICS INC
https://preludetx.com
$254.5M
Market Cap
-$77.8M
Net Income
Sector: Healthcare
Industry: Biotechnology
175 Innovation Boulevard, Wilmington, DE, United States, 19805
302 467 1280

Prelude Therapeutics Incorporated, a clinical-stage precision oncology company, focuses on the discovery and development of novel precision cancer medicines to underserved patients. It is developing JAK2V617F, a driver mutation product for the treatment of myeloproliferative neoplasms, myelofibrosis (MF), polycythemia vera, and essential thrombocythemia (ET); KAT6A for the treatment of advanced breast cancer and other solid tumors; and mutated calreticulin degrader antibody conjugates to treat MF and ET. The company has collaboration with AbCellera Biologics to discover, develop, and commercialize novel degrader antibody conjugates. Prelude Therapeutics Incorporated was incorporated in 2016 and is based in Wilmington, Delaware.

Key Executives

  • Krishna Vaddi
  • Bryant David Lim
  • Peggy A. Scherle
  • Andrew Combs
  • Sean Brusky

Current Ownership Distribution

  • Institutions604.7M (84.28%)
  • Mutual Funds77.7M (10.83%)
  • Insiders35.1M (4.89%)
  • Other0 (0.00%)