UPB
UPSTREAM BIO (UPB)
NASDAQ
$6.33+$0.03 (+0.40%)
Price as of Jun 23, 2026 1:34 PM EDT
  • $342.8M
    Market Cap
  • -41.23%
    1-Year Change
  • Biotechnology
    Industry
Annual
Quarterly
12/31/2025
12/31/2024
Income Statement
Total Operating Revenue
2.9M
+20.42%
2.4M
N/A
Cost of Revenue
N/A
N/A
N/A
N/A
Gross Profit
2.9M
+20.42%
2.4M
N/A
Sales and Marketing Expense
N/A
N/A
N/A
N/A
Research and Development Expense
-136.8M
+117.27%
-63.0M
N/A
Depreciation and Amortization Expense
188,000
+111.24%
89,000
N/A
Total Operating Expenses
163.2M
+103.68%
80.1M
N/A
Operating Profit
-160.4M
+106.21%
-77.8M
N/A
Interest Income
16.9M
+39.68%
12.1M
N/A
Interest Expense
N/A
N/A
N/A
N/A
Interest Income and Expense and Net
16.9M
+39.68%
12.1M
N/A
Total Nonoperating Income and Expense
16.9M
+13.10%
15.0M
N/A
Income before Taxes
-143.4M
+87.76%
-76.4M
N/A
Income Taxes
0
N/A
0
N/A
Extraordinary Items
N/A
N/A
N/A
N/A
Net Income
-143.4M
+128.39%
-62.8M
N/A
Net Income from Continuing Operations Applicable to Common
-143.4M
+87.76%
-76.4M
N/A
Basic EPS and Net Income
-2.66
-52.33%
-5.58
N/A
Diluted EPS and Net Income
-2.66
-52.33%
-5.58
N/A
Basic Weighted Average Shares
53.9M
+293.59%
13.7M
N/A
Diluted Weighted Average Shares
53.9M
+293.59%
13.7M
N/A
Balance Sheet
Cash and Cash Equivalents
101.6M
-68.83%
325.9M
N/A
Short-Term Investments
239.9M
+65.97%
144.6M
N/A
Cash and Cash Equivalents and Short-Term Investments
341.5M
-27.41%
470.5M
N/A
Total Current Assets
351.8M
-26.58%
479.2M
N/A
Accumulated Depreciation
344,000
+120.51%
156,000
N/A
Property and Plant and Equipment and Net
559,000
-3.95%
582,000
N/A
Total Long-Term Assets
559,000
-3.95%
582,000
N/A
Total Assets
353.8M
-26.56%
481.7M
N/A
Income Taxes Payable
N/A
N/A
N/A
N/A
Total Short-Term Debt
200,000
0.00%
200,000
N/A
Total Current Liabilities
13.5M
+25.29%
10.7M
N/A
Total Long-Term Debt
N/A
N/A
N/A
N/A
Total Long-Term Liabilities
549,000
-51.42%
1.1M
N/A
Total Liabilities
14.0M
+17.98%
11.9M
N/A
Retained Earnings
-334.2M
+75.19%
-190.8M
N/A
Total Stockholders Equity
339.8M
-27.69%
469.9M
N/A
Total Shares Outstanding
54.2M
+1.18%
53.6M
N/A
Cash Flow
Cash from Operating Activities
-133.3M
+125.23%
-59.2M
N/A
Capital Expenditures
165,000
-67.71%
511,000
N/A
Cash from Investing Activities
-93.5M
+57.15%
-59.5M
N/A
Dividends Paid
N/A
N/A
N/A
N/A
Cash from Financing Activities
2.4M
-99.42%
418.9M
N/A
Financials Ratio
Gross Margin
N/A
N/A
N/A
N/A
Operating Margin
-5,618.82%
N/A
N/A
N/A
Return on Assets
-34.34%
N/A
N/A
N/A
Return on Equity
-35.43%
N/A
N/A
N/A
Revenue Growth
20.42%
N/A
N/A
N/A
Current Ratio
26.15
N/A
N/A
N/A
Cash Ratio
7.55
N/A
N/A
N/A
Debt-to-Equity Ratio
N/A
N/A
N/A
N/A
Debt-to-Assets Ratio
N/A
N/A
N/A
N/A

Earnings & Revenue History

Debt-to-Assets

Cash Flow