ZYME
ZYMEWORKS (ZYME)
NASDAQ
$23.86+$0.59 (+2.56%)
Price as of Jun 23, 2026 4:10 PM EDT
  • $1.7B
    Market Cap
  • 86.53%
    1-Year Change
  • Biotechnology
    Industry

Key Performance

More
  • Earnings Score: 27
  • Momentum Score: 91
  • True Yield: N/A
  • Financial Health Score: 8
TradeSmith Loading

Latest Research & News

Zymeworks Presents New Phase 1 Data for Folate Receptor Alpha-Targeting ADC ZW191 at ESMO Gynaecological Cancers Congress 2026

Zymeworks presented Phase 1 data for ZW191, a folate receptor alpha-targeting antibody-drug conjugate, showing a confirmed objective response rate of 78.6% in FRα-positive platinum-resistant ovarian cancer patients and 47.4% in FRα-negative patients. The drug demonstrated a favorable tolerability profile with median progression-free survival of 7.6 months across ovarian and endometrial cancer cohorts. Patient recruitment in dose optimization cohorts has been completed, supporting continued clinical development.

06/14/2026, 6:05 PM • GlobeNewswire

Zymeworks Announces Participation in Upcoming Investor Conferences

Zymeworks Inc. announced its participation in three upcoming investor conferences: the 2026 Stifel Virtual Targeted Oncology Forum (May 20), TD Cowen 7th Annual Oncology Innovation Summit (May 27), and 2026 Jefferies Global Healthcare Conference (June 3). The company will engage in fireside chats and one-on-one meetings to discuss its portfolio of licensed healthcare assets and pipeline of novel biotherapeutics.

05/13/2026, 6:00 AM • GlobeNewswire

Zymeworks Presents New Preclinical Data at AACR 2026 Highlighting Broad Antibody-Drug Conjugate Programs Including Novel RAS-Targeting Platform

Zymeworks announced six poster presentations at AACR 2026 showcasing preclinical data from its antibody-drug conjugate (ADC) pipeline, including novel RAS-targeting platforms and multiple first-in-class programs. The company highlighted efficacy and favorable tolerability across solid tumor models, with clinical data from the Phase 1 ZW191 trial to be presented in an oral presentation on April 21.

04/17/2026, 3:00 PM • GlobeNewswire

Zymeworks Announces Additional Leadership Appointments to Advance Next Phase of Growth

Zymeworks Inc. announced the full-time appointments of Dr. Adam Schayowitz as Executive Vice President and Head of R&D, and Scott Platshon as Executive Vice President and Chief Business Officer, effective April 9, 2026. Both executives, previously in interim roles, will report to CEO Kenneth Galbraith. The appointments come as Zymeworks focuses on executing its pipeline strategy, managing licensed assets including Ziihera® (zanidatamab-hrii) and pasritamig, and advancing its asset aggregation strategy to drive long-term shareholder value.

04/09/2026, 6:00 AM • GlobeNewswire

Zymeworks Appoints Kristin Stafford as Chief Financial Officer

Zymeworks Inc. announced the appointment of Kristin Stafford as Chief Financial Officer effective April 1, 2026. Stafford brings extensive experience from Royalty Pharma in strategic planning, capital allocation, and executing complex transactions. The appointment comes as Zymeworks continues advancing its pipeline of biotherapeutics and executing strategic priorities.

04/01/2026, 6:00 AM • GlobeNewswire

Zymeworks Receives U.S. FDA Fast Track Designation for ZW191, an FRα-Targeting Antibody-Drug Conjugate

Zymeworks Inc. announced that the U.S. FDA has granted Fast Track designation to ZW191, an antibody-drug conjugate targeting folate receptor-α (FRα) for treating advanced or metastatic platinum-resistant ovarian cancer. The designation expedites development and review timelines for drugs addressing serious conditions with unmet medical needs. ZW191 is currently in Phase 1 clinical trials evaluating safety, tolerability, and anti-tumor activity in patients with advanced solid tumors.

03/30/2026, 6:00 AM • GlobeNewswire

Zymeworks Announces Participation in Upcoming Investor Conferences

Zymeworks Inc. announced that management will participate in upcoming investor conferences including the Needham 25th Annual Virtual Healthcare Conference on April 15 and the 2026 Bloom Burton & Co. Healthcare Investor Conference on April 21 in Toronto. The company will present clinical and preclinical data on its pipeline programs.

03/24/2026, 6:00 AM • GlobeNewswire

Zymeworks To Report Fourth Quarter and Full Year 2025 Financial Results and Host Conference Call on March 2, 2026

Zymeworks Inc. announced it will report its fourth quarter and full year 2025 financial results on March 2, 2026, followed by a conference call at 8:30 am ET. The biotechnology company is managing a portfolio of licensed healthcare assets and developing multifunctional biotherapeutics, with key products including Ziihera and partnerships with BeOne Medicines and Jazz Pharmaceuticals for commercialization rights.

02/12/2026, 6:00 AM • GlobeNewswire

Zymeworks Announces Participation in Upcoming Investor Conferences

Zymeworks Inc. announced that its management will participate in multiple investor conferences in February and March 2026, including Citi's Virtual Oncology Leadership Summit, TD Cowen Health Care Conference, Leerink Global Healthcare Conference, and Citizens Life Science Conference. The company continues to advance its portfolio of licensed healthcare assets and biotherapeutics pipeline.

01/27/2026, 6:00 AM • GlobeNewswire

Jazz Pharmaceuticals' Drug Extends Survival Past Two Years in Advanced Stomach Cancer Trial

Jazz Pharmaceuticals announced positive Phase 3 trial results for Ziihera (zanidatamab-hrii) in treating HER2-positive gastroesophageal adenocarcinoma. The triplet therapy combining Ziihera with tislelizumab and chemotherapy achieved a median overall survival of 26.4 months, the longest reported in a Phase 3 GEA trial, representing a 28% reduction in death risk. The doublet therapy also showed strong results with median OS of 24.4 months. Jazz shares rose 2.07% following the announcement.

01/07/2026, 1:12 PM • Benzinga

Ziihera® (zanidatamab-hrii) Combinations Achieve Unprecedented Results in First-Line HER2+ Locally Advanced or Metastatic GEA including more than Two Years Median Overall Survival Benefit

Zymeworks announced positive Phase 3 HERIZON-GEA-01 results for Ziihera (zanidatamab-hrii) in combination with chemotherapy, with or without tislelizumab, for first-line treatment of HER2-positive gastroesophageal adenocarcinoma. The trial demonstrated statistically significant improvements in progression-free survival (approximately 35% risk reduction) and overall survival (26.4 months median, representing a 7+ month improvement over trastuzumab). Zymeworks is eligible to receive up to $440 million in milestone payments from regulatory approvals across major markets.

01/06/2026, 1:34 PM • GlobeNewswire

Zymeworks Announces Participation in Upcoming Investor Conferences

Zymeworks Inc. will participate in two upcoming healthcare investor conferences in Miami, including one-on-one meetings and fireside chats, highlighting their biotechnology portfolio and licensed healthcare assets.

11/24/2025, 6:00 AM • GlobeNewswire

Zymeworks, Jazz Pharmaceuticals Stocks Climb On Robust Gastroesophageal Trial Outcomes And Upcoming Regulatory Plans

Zymeworks, Jazz Pharmaceuticals, and BeOne Medicines reported positive Phase 3 trial results for Ziihera in treating HER2-positive gastroesophageal adenocarcinoma, demonstrating significant improvements in progression-free and overall survival.

11/17/2025, 12:09 PM • Benzinga

Zymeworks Announces Participation in Upcoming Investor Conferences

Zymeworks, a clinical-stage biotechnology company, announced participation in upcoming investor conferences and highlighted its progress in developing biotherapeutics for cancer and other diseases, including the FDA-approved zanidatamab for biliary tract cancer.

10/28/2025, 6:00 AM • GlobeNewswire

Zymeworks to Report Third Quarter 2025 Financial Results and Host Conference Call on November 6, 2025

Zymeworks will report its Q3 2025 financial results on November 6, 2025, and host a conference call to discuss financial performance and provide a corporate update.

10/16/2025, 6:00 AM • GlobeNewswire

Peers

Statistics

More
Day Range
$23.05
$23.62
$23.26
1-Year Range
$12.02
$28.56
$23.26
Latest Close$23.26
Change
+$0.12 (+0.52%)
Volume530,630
Market Cap$1.7B
Shares Outstanding73.0M
P/E (TTM)-17.06
Diluted EPS (TTM)-$1.36
Enterprise Value$1.9B

Information as of 06/22/2026

Company Profile

$1.7B
Market Cap
-$102.7M
Net Income
Sector: Healthcare
Industry: Biotechnology
108 Patriot Drive, Middletown, DE, United States, 19709
302 274 8744

Zymeworks Inc., a biotechnology company, develops biotherapeutics for the treatment of cancer, inflammation, and autoimmune diseases. The company's platforms include Azymetric multispecific antibody platform; Drug Conjugate platform that includes a suite of proprietary cytotoxins comprising topoisomerase and microtubulin inhibiting toxins, stable linkers, and conjugation technologies; EFECT platform, which consists of a set of modifications to the Fc region of antibodies; and ProTECT, a tumor-specific immune co-stimulation platform. Its lead product candidates include Ziihera (zanidatamab-hrii), a bispecific antibody targeting HER2-expressing tumors; zanidatamab for the treatment of neoadjuvant populations, breast cancer, and other HER2-expressing cancers; Pasritamig, a bispecific T cell engager targeting human kallikrein 2 for the treatment monotherapy and castration resistant prostate cancer; ZW191, a clinical- antibody-drug conjugates (ADC) that targets folate receptor alpha expressing tumors, including ovarian, endometrial, and non-small cell lung cancers; ZW251, a clinical-stage ADC molecule for the treatment of glypican 3 expressing hepatocellular carcinoma; ZW220, an ADC that targets NaPi2b-expressing NSCLC and ovarian cancer; ZW209, a novel TriTCE targeting Delta-like ligand 3 -expressing tumor cells for the treatment of solid tumors; and ZW1528, a bispecific molecule to treat chronic obstructive pulmonary disease. It has strategic partnerships and collaborations with Jazz Pharmaceuticals plc; Bristol- Myers Squibb company; Celgene Alpine Investment Co. LLC; GlaxoSmithKline Intellectual Property Development Limited; Daiichi Sankyo Co., Ltd.; Merck Sharp & Dohme Research GmbH; and Janssen Biotech, Inc. Zymeworks Inc. was incorporated in 2003 and is based in Middletown, Delaware.

Key Executives

  • Kenneth H. Galbraith
  • Paul Moore
  • Bijal Desai
  • Kristin Stafford
  • Diana Papove

Current Ownership Distribution

  • Institutions665.2M (78.59%)
  • Mutual Funds131.9M (15.59%)
  • Insiders49.3M (5.82%)
  • Other0 (0.00%)