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- $145.7MMarket Cap
- -32.40%1-Year Change
- BiotechnologyIndustry
AGENUS (AGEN)
Key Performance
More- Earnings Score: N/A
- Momentum Score: 69
- True Yield: N/A
- Financial Health Score: N/A
Latest Research & News
A comprehensive market report reveals over 40 companies developing 50+ CTLA-4 inhibitor drugs for cancer immunotherapy. Key developments include FDA approvals for tremelimumab in hepatocellular cancer and MT-8421 for solid tumors, along with promising clinical progress from multiple biopharmaceutical companies in checkpoint inhibitor combinations and bispecific antibodies.
02/18/2026, 11:00 AM • GlobeNewswire
Agenus (AGEN) Q3 2024 Earnings Call Transcript
Agenus reported Q3 2024 results highlighting groundbreaking clinical progress with BOT/BAL immunotherapy in hard-to-treat cancers, particularly microsatellite-stable colorectal cancer. However, the company faces significant financial constraints with only $44.8 million in cash at quarter-end. Management is pursuing cost reductions, real estate asset monetization ($45M+ in properties), and strategic partnerships to fund Phase 3 trials and extend runway. Multiple data presentations from neoadjuvant trials are expected in early 2025.
01/05/2026, 6:04 PM • The Motley Fool
FDA Tightens Survival Standards as Cancer Drug Pipeline Hits $866B Market Milestone
The FDA is tightening survival standards in cancer research, with private investments helping to fill public funding gaps. Several biotech companies are advancing innovative immunotherapies, with Oncolytics Biotech showing promising results in pancreatic cancer treatment.
08/28/2025, 10:44 AM • Benzinga
PD-(L)1 inhibitors are projected to dominate future drug sales, revolutionizing cancer care across multiple tumor types with flexible treatment approaches and promising clinical outcomes.
08/18/2025, 1:00 PM • GlobeNewswire
U.S. Pharmaceutical CDMO Market Valuation to Surpass USD 68.57 Billion by 2034
The U.S. pharmaceutical Contract Development and Manufacturing Organization (CDMO) market is expected to grow from $36.77 billion in 2024 to $68.57 billion by 2034, driven by increased demand for specialized pharmaceutical services, technological advancements, and growing needs in oncology and complex drug development.
08/13/2025, 10:00 AM • GlobeNewswire
Biotech Underdogs Line Up for Pivotal Shots at Game-Changing Cancer Treatments
Several biotech companies are developing innovative cancer treatments, with promising clinical trial results in various cancer types, focusing on immunotherapy and personalized medicine approaches.
07/29/2025, 3:46 PM • Benzinga
Peers
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MoreInformation as of 06/03/2026
Company Profile
Agenus Inc., a clinical-stage biotechnology company, discovers and develops immunotherapies for cancer and infectious diseases in the United States and internationally. It offers Retrocyte Display, an antibody expression platform for the identification of fully human and humanized monoclonal antibodies; and display technologies. It develops QS-21 Stimulon adjuvant, a saponin-based vaccine adjuvant. The company also develops Balstilimab, a programmed death receptor-1 (PD-1) blocking antibody; AGEN1181, a human Fc-enhanced cytotoxic T-lymphocyte antigen 4 (CTLA-4) blocking antibody that is in Phase 2 trials in metastatic colorectal cancer (mCRC), pancreatic cancer, and melanoma; AGEN2373, a CD137 monospecific antibody that is in Phase 1b clinical trial; AGEN1423, a CD73/TGFß TRAP antibody; AGEN1571, an ILT2 monospecific antibody that is in clinical development; and BMS-986442, a TIGIT bispecific antibodies. In addition, it develops INCAGN1876, a GITR agonist; INCAGN2390, a TIM-3 monoclonal antibodies; INCAGN2385, a LAG-3 monospecific antibody; MK-4830, a monospecific antibody targeting ILT4 that is in Phase 2 clinical trial; and AGEN1884. The company operates under the Agenus, MiNK, Prophage, Retrocyte Display, and STIMULON trademarks. It has collaborations with Bristol-Myers Squibb Company, Betta Pharmaceuticals Co., Ltd., UroGen Pharma Ltd., Gilead Sciences, Inc., Incyte Corporation, and Merck Sharp & Dohme. The company was formerly known as Antigenics Inc. and changed its name to Agenus Inc. in January 2011. Agenus Inc. was founded in 1994 and is headquartered in Lexington, Massachusetts.
Key Executives
- Garo H. Armen
- Steven J. O'Day
- Jennifer S. Buell
- Tracy Mazza Clemente
- Todd Jude Yancey
Current Ownership Distribution
- Institutions1.9B (71.00%)
- Mutual Funds730.6M (26.94%)
- Insiders55.8M (2.06%)
- Other0 (0.00%)