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Ionis Pharmaceut (IONS)
NASDAQ
$75.98+$0.08 (+0.11%)
Price as of Jun 23, 2026 4:15 PM EDT- $12.5BMarket Cap
- 101.46%1-Year Change
- BiotechnologyIndustry
Ionis Pharmaceut (IONS)
$75.98+$0.08 (+0.11%)
Annual
Quarterly
12/31/2025 | 12/31/2024 | 12/31/2023 | 12/31/2022 | ||
|---|---|---|---|---|---|
Income Statement | |||||
Total Operating Revenue | 9.3M -98.68% | 705.1M -10.48% | 787.6M +34.10% | 587.4M -27.53% | |
Cost of Revenue | 15.9M +41.85% | 11.2M +22.80% | 9.1M -35.30% | 14.1M +30.20% | |
Gross Profit | -6.6M -100.96% | 693.9M -10.87% | 778.5M +35.81% | 573.3M -28.31% | |
Sales and Marketing Expense | 393.9M +47.25% | 267.5M +14.98% | 232.6M +54.77% | 150.3M -19.35% | |
Research and Development Expense | -915.6M +1.56% | -901.5M +0.21% | -899.6M +7.98% | -833.1M +29.48% | |
Depreciation and Amortization Expense | 2.4M +4.41% | 2.3M -8.71% | 2.6M +5.96% | 2.4M +2.68% | |
Total Operating Expenses | 1.3B +12.30% | 1.2B +3.40% | 1.1B +14.42% | 997.6M +18.67% | |
Operating Profit | -381.7M -19.66% | -475.1M +34.31% | -353.7M -13.76% | -410.2M +1,258.88% | |
Interest Income | 10.2M +453.76% | -2.9M +50.94% | -1.9M -73.90% | -7.3M -172.58% | |
Interest Expense | -17.3M +1.58% | -17.0M +34.23% | -12.7M +55.87% | -8.1M -13.12% | |
Interest Income and Expense and Net | -7.0M -64.58% | -19.9M +36.43% | -14.6M -5.70% | -15.5M -2,149.73% | |
Total Nonoperating Income and Expense | -15.4M -1,243.56% | 1.3M -90.58% | 14.3M +295.99% | -7.3M +542.01% | |
Income before Taxes | -379.6M -17.49% | -460.1M +37.76% | -334.0M +29.45% | -258.0M +785.09% | |
Income Taxes | 1.8M +128.94% | -6.2M -119.09% | 32.3M +175.38% | 11.7M +2,230.13% | |
Extraordinary Items | N/A N/A | N/A N/A | N/A N/A | N/A N/A | |
Net Income | -381.4M -15.97% | -453.9M +23.92% | -366.3M +35.80% | -269.7M +843.18% | |
Net Income from Continuing Operations Applicable to Common | -379.6M -17.49% | -460.1M +37.76% | -334.0M +29.45% | -258.0M +785.09% | |
Basic EPS and Net Income | -2.38 -21.71% | -3.04 +18.75% | -2.56 +34.74% | -1.90 +850.00% | |
Diluted EPS and Net Income | -2.38 -21.71% | -3.04 +18.75% | -2.56 +34.74% | -1.90 +850.00% | |
Basic Weighted Average Shares | 160.0M +7.02% | 149.5M +4.42% | 143.2M +0.95% | 141.8M +0.59% | |
Diluted Weighted Average Shares | 160.0M +7.02% | 149.5M +4.42% | 143.2M +0.95% | 141.8M +0.59% | |
Balance Sheet | |||||
Cash and Cash Equivalents | 372.3M +53.78% | 242.1M -39.37% | 399.3M +44.41% | 276.5M -68.19% | |
Short-Term Investments | 2.3B +12.14% | 2.1B +6.40% | 1.9B +12.95% | 1.7B +37.30% | |
Cash and Cash Equivalents and Short-Term Investments | 2.7B +16.53% | 2.3B -1.44% | 2.3B +17.33% | 2.0B -6.06% | |
Total Current Assets | 3.0B +14.13% | 2.6B -0.82% | 2.6B +19.94% | 2.2B -6.07% | |
Accumulated Depreciation | 109.1M +2.60% | 106.3M +9.88% | 96.8M +10.31% | 87.7M -14.55% | |
Property and Plant and Equipment and Net | 123.0M +30.55% | 94.3M +32.67% | 71.0M -4.38% | 74.3M -58.28% | |
Total Long-Term Assets | 171.6M +34.83% | 127.3M +20.89% | 105.3M +39.73% | 75.3M +26.49% | |
Total Assets | 3.5B +17.32% | 3.0B +0.45% | 3.0B +18.00% | 2.5B -2.98% | |
Income Taxes Payable | 2.7M +7,879.41% | 34,000 -98.42% | 2.2M -65.58% | 6.2M +17,258.33% | |
Total Short-Term Debt | 431.9M N/A | 0 -100.00% | 44.3M +29,258.94% | 151,000 N/A | |
Total Current Liabilities | 781.6M +152.67% | 309.3M -30.97% | 448.1M +43.82% | 311.6M +29.52% | |
Total Long-Term Debt | 779.6M -37.40% | 1.2B +1.30% | 1.2B +4.59% | 1.2B -3.73% | |
Total Long-Term Liabilities | 354.4M +11.33% | 318.3M -22.75% | 412.1M +5,682.47% | 7.1M -97.97% | |
Total Liabilities | 3.0B +25.65% | 2.4B -7.22% | 2.6B +32.76% | 2.0B +6.58% | |
Retained Earnings | -2.6B +19.60% | -2.2B +22.50% | -1.8B +25.62% | -1.4B +23.25% | |
Total Stockholders Equity | 489.1M -18.49% | 600.0M +55.16% | 386.7M -32.50% | 572.9M -25.77% | |
Total Shares Outstanding | 163.3M +3.42% | 157.9M +9.40% | 144.3M +1.61% | 142.1M +0.60% | |
Cash Flow | |||||
Cash from Operating Activities | -268.6M -46.38% | -500.9M +62.90% | -307.5M +12.08% | -274.4M -990.84% | |
Capital Expenditures | 51.4M +13.61% | 45.3M +90.21% | 23.8M +51.42% | 15.7M +31.50% | |
Cash from Investing Activities | -277.8M +107.25% | -134.0M -37.41% | -214.1M -18.47% | -262.6M -234.75% | |
Dividends Paid | N/A N/A | N/A N/A | N/A N/A | N/A N/A | |
Cash from Financing Activities | 675.8M +41.37% | 478.1M -25.78% | 644.1M +1,264.81% | -55.3M -122.48% | |
Financials Ratio | |||||
Gross Margin | -71.43% -172.59% | 98.41% -0.44% | 98.84% +1.27% | 97.60% -1.08% | |
Operating Margin | -4,112.97% +6,004.67% | -67.37% +50.02% | -44.91% -35.69% | -69.84% +1,774.98% | |
Return on Assets | -11.69% -22.85% | -15.15% +14.21% | -13.26% +26.50% | -10.48% +816.81% | |
Return on Equity | -70.04% -23.88% | -92.00% +20.51% | -76.34% +90.29% | -40.12% +1,032.91% | |
Revenue Growth | -98.68% +842.05% | -10.48% -130.72% | 34.10% +223.87% | -27.53% -347.24% | |
Current Ratio | 3.83 -54.83% | 8.47 +43.68% | 5.90 -16.61% | 7.07 -27.48% | |
Cash Ratio | 0.48 -39.14% | 0.78 -12.17% | 0.89 +0.41% | 0.89 -75.44% | |
Debt-to-Equity Ratio | 2.48 +19.34% | 2.08 -36.99% | 3.29 +60.51% | 2.05 +29.70% | |
Debt-to-Assets Ratio | 0.34 -17.10% | 0.41 -2.65% | 0.43 -8.19% | 0.46 -0.77% | |
Earnings & Revenue History
Debt-to-Assets
Cash Flow