KPTI
KARYOPHARM THER (KPTI)
NASDAQ
$9.02+$0.02 (+0.17%)
Price as of Jun 03, 2026 6:03 PM EDT
  • $206.2M
    Market Cap
  • 117.18%
    1-Year Change
  • Biotechnology
    Industry
Annual
Quarterly
12/31/2025
12/31/2024
12/31/2023
12/31/2022
Income Statement
Total Operating Revenue
114.9M
-20.92%
145.2M
-0.55%
146.0M
-7.03%
157.1M
-25.14%
Cost of Revenue
5.9M
+2,520.70%
227,000
-95.41%
4.9M
-5.20%
5.2M
+53.23%
Gross Profit
108.9M
-24.90%
145.0M
+2.78%
141.1M
-7.09%
151.9M
-26.43%
Sales and Marketing Expense
105.2M
-8.86%
115.4M
-12.47%
131.9M
-9.30%
145.4M
+1.08%
Research and Development Expense
-125.6M
-12.30%
-143.2M
+3.23%
-138.8M
-6.67%
-148.7M
-7.57%
Depreciation and Amortization Expense
296,000
-12.94%
340,000
-35.85%
530,000
-14.65%
621,000
-21.29%
Total Operating Expenses
236.8M
-10.54%
264.7M
-3.95%
275.6M
-7.92%
299.3M
-2.86%
Operating Profit
-90.7M
-24.06%
-119.4M
-7.79%
-129.5M
-8.90%
-142.2M
+44.70%
Interest Income
2.8M
-62.53%
7.4M
-32.38%
10.9M
+363.88%
2.4M
+305.33%
Interest Expense
-2.7M
0.00%
-2.7M
-88.52%
-23.8M
-4.69%
-25.0M
-4.03%
Interest Income and Expense and Net
37,000
-99.21%
4.7M
+136.21%
-12.9M
-43.10%
-22.6M
-11.10%
Total Nonoperating Income and Expense
-105.3M
-344.41%
43.1M
+425.46%
-13.2M
-41.74%
-22.7M
-11.07%
Income before Taxes
-196.0M
+156.66%
-76.4M
-46.51%
-142.8M
-13.43%
-164.9M
+33.19%
Income Taxes
43,000
-24.56%
57,000
-82.35%
323,000
-12.47%
369,000
+37.69%
Extraordinary Items
N/A
N/A
N/A
N/A
N/A
N/A
N/A
N/A
Net Income
-196.0M
+156.52%
-76.4M
-46.60%
-143.1M
-13.43%
-165.3M
+33.20%
Net Income from Continuing Operations Applicable to Common
-196.0M
+156.66%
-76.4M
-46.51%
-142.8M
-13.43%
-164.9M
+33.19%
Basic EPS and Net Income
-17.93
+2,746.03%
-0.63
-49.60%
-1.25
-38.12%
-2.02
+22.42%
Diluted EPS and Net Income
-17.93
+1,827.96%
-0.93
-25.60%
-1.25
-38.12%
-2.02
+22.42%
Basic Weighted Average Shares
10,935
-91.03%
121,863
-99.89%
114.2M
+39.51%
81.9M
+8.84%
Diluted Weighted Average Shares
10,935
-91.38%
126,809
-99.89%
114.2M
+39.51%
81.9M
+8.84%
Balance Sheet
Cash and Cash Equivalents
60.5M
-3.10%
62.5M
+19.61%
52.2M
-61.36%
135.2M
-29.02%
Short-Term Investments
3.2M
-93.07%
46.2M
-66.79%
139.2M
-2.50%
142.8M
+274.20%
Cash and Cash Equivalents and Short-Term Investments
63.7M
-41.36%
108.7M
-43.21%
191.4M
-31.13%
278.0M
+21.59%
Total Current Assets
103.1M
-34.09%
156.5M
-33.10%
233.9M
-33.20%
350.2M
+27.05%
Accumulated Depreciation
5.5M
-17.65%
6.7M
+1.92%
6.6M
-1.20%
6.6M
+9.71%
Property and Plant and Equipment and Net
104,000
-74.00%
400,000
-33.99%
606,000
-46.80%
1.1M
-30.63%
Total Long-Term Assets
267,000
-79.99%
1.3M
0.00%
1.3M
N/A
0
-100.00%
Total Assets
108.4M
-34.06%
164.4M
-31.62%
240.4M
-32.87%
358.2M
+17.32%
Income Taxes Payable
N/A
N/A
N/A
N/A
N/A
N/A
N/A
N/A
Total Short-Term Debt
21.0M
N/A
N/A
N/A
N/A
N/A
N/A
N/A
Total Current Liabilities
92.1M
-0.22%
92.3M
+32.79%
69.5M
+5.42%
65.9M
-10.59%
Total Long-Term Debt
94.8M
+0.20%
94.6M
-44.65%
170.9M
+0.48%
170.1M
+0.48%
Total Long-Term Liabilities
11.1M
+356.58%
2.4M
+148.47%
978,000
-83.96%
6.1M
-32.02%
Total Liabilities
401.3M
+14.53%
350.4M
-6.96%
376.6M
+0.48%
374.8M
-2.64%
Retained Earnings
-1.8B
+12.54%
-1.6B
+5.14%
-1.5B
+10.65%
-1.3B
+14.02%
Total Stockholders Equity
-292.9M
+57.47%
-186.0M
+36.57%
-136.2M
+717.76%
-16.7M
-79.09%
Total Shares Outstanding
18.3M
-85.49%
126.2M
+9.82%
114.9M
+1.50%
113.2M
+49.46%
Cash Flow
Cash from Operating Activities
-75.4M
-40.88%
-127.5M
+37.49%
-92.7M
-38.00%
-149.6M
+39.62%
Capital Expenditures
0
-100.00%
142,000
N/A
0
-100.00%
118,000
-44.34%
Cash from Investing Activities
43.4M
-54.57%
95.5M
+1,102.43%
7.9M
+107.62%
-104.3M
-173.50%
Dividends Paid
N/A
N/A
N/A
N/A
N/A
N/A
N/A
N/A
Cash from Financing Activities
30.0M
-27.85%
41.6M
+3,605.16%
1.1M
-99.42%
193.7M
+163.06%
Financials Ratio
Gross Margin
94.82%
-5.03%
99.84%
+3.34%
96.62%
-0.07%
96.68%
-1.73%
Operating Margin
-78.97%
-3.97%
-82.24%
-7.29%
-88.71%
-2.02%
-90.53%
+93.30%
Return on Assets
-143.71%
+280.65%
-37.75%
-21.04%
-47.81%
-4.04%
-49.83%
+24.15%
Return on Equity
81.86%
+72.58%
47.43%
-74.66%
187.23%
-45.44%
343.18%
-59.72%
Revenue Growth
-20.92%
+3,737.37%
-0.55%
-92.25%
-7.03%
-72.04%
-25.14%
-126.71%
Current Ratio
1.12
-33.94%
1.70
-49.62%
3.37
-36.63%
5.31
+42.11%
Cash Ratio
0.66
-2.88%
0.68
-9.94%
0.75
-63.35%
2.05
-20.61%
Debt-to-Equity Ratio
-0.40
N/A
N/A
N/A
N/A
N/A
N/A
N/A
Debt-to-Assets Ratio
1.07
N/A
N/A
N/A
N/A
N/A
N/A
N/A

Earnings & Revenue History

Debt-to-Assets

Cash Flow